Table 2. Clinical and laboratory variables according to MCP-1 genotypes.
| Variables | All children (n = 174) |
AA+AG (n = 104) |
GG (n = 70) |
P value | |
|---|---|---|---|---|---|
| Age (years)‡ | 9 (6-11) | 9 (6-11) | 9 (6-11) | 0.39 | |
| Gender % (n)* | 0.42 | ||||
| Male | 50.6 (88) | 48.1 (50) | 54.3 (38) | ||
| Female | 49.4 (86) | 51.9 (54) | 45.7 (32) | ||
| Weight (kg)‡ | 34.1 (20.1-59.2) | 32.1 (20.3-59.1) | 36.2 (20.1-64.9) | 0.13 | |
| Height (cm)† | 133.4 ± 11.5 | 132.6 ± 11.1 | 134.6 ± 12.2 | 0.26 | |
| BMI (kg/m2)‡ | 18.9 (14.3-28.2) | 18.4 (14.3-25.9) | 19.7 (14.5-29.1) | 0.08 | |
| Obesity % (n)* | 0.57 | ||||
| No | 51.1 (89) | 53 (55) | 49 (34) | ||
| Yes | 48.9 (85) | 47 (49) | 51 (36) | ||
| Waist circumference (cm)‡ | 67.5 (54-90) | 67 (54-89) | 70 (56-94) | 0.10 | |
| Hip circumference (cm)‡ | 76 (62-96.5) | 74 (62-96) | 79 (62-96.5) | 0.15 | |
| Waist-to-hip ratio‡ | 0.9 (0.8-0.97) | 0.9 (0.8-0.97) | 0.9 (0.8-0.97) | 0.24 | |
| Arm circumference (cm)‡ | 21 (16-29) | 21 (16.5-28) | 22 (16-30) | 0.20 | |
| Biceps skinfold (mm)† | 15.6 ± 4.6 | 15.7 ± 4.9 | 15.5 ± 4.1 | 0.76 | |
| Triceps skinfold (mm)‡ | 15 (8.5-21.5) | 15 (8.5-21) | 15 (7.5-22) | 0.97 | |
| Subscapular skinfold (mm)‡ | 13 (6-22.5) | 12.8 (5.5-21.5) | 13.5 (6-23) | 0.65 | |
| Suprailiac skinfold (mm)† | 18.2 ± 5.6 | 18.1 ± 5.5 | 18.2 ± 5.9 | 0.95 | |
| SBP (mmHg)‡ | 98 (80-115) | 98 (80-117) | 98 (81-110) | 0.82 | |
| DBP (mmHg)‡ | 58 (49-71) | 58 (49-72) | 58.5 (50-70) | 0.83 | |
| Hypertension % (n)* | 0.47 | ||||
| No | 92.5 (161) | 91.3 (95) | 94.3 (66) | ||
| Yes | 7.5 (13) | 8.7 (9) | 5.7 (4) | ||
| Glucose (mg/dL)‡ | 96 (73-109) | 96.5 (72-109) | 95.5 (78-112) | 0.71 | |
| Insulin (µU/mL)‡ | 6.9 (0.8-22.4) | 6.6 (1.0-21.5) | 8.2 (0.8-22.4) | 0.17 | |
| HOMA-IR‡ | 1.7 (0.2-5.5) | 1.5 (0.2-4.8) | 1.9 (0.2-5.8) | 0.15 | |
| Insulin resistance % (n)* | 0.04 | ||||
| No | 67.2 (117) | 73.1 (76) | 58.6 (41) | ||
| Yes | 32.8 (57) | 26.9 (28) | 41.4 (29) | ||
| hsCRP (mg/L)‡ | 0.8 (0.1-6.5) | 0.8 (0.1-8.0) | 0.9 (0.1-6.3) | 0.99 | |
| Leukocytes (103/mm3)‡ | 7.6 (4.8-11.5) | 7.7 (4.8-12.3) | 7.6 (5.1-11.2) | 0.64 | |
| Platelets (103/mm3)‡ | 308 (219-412) | 310.5 (224-413) | 306 (205-410) | 0.66 | |
*
Values are expressed as percentages and n. Chi-square test.
†
Values are expressed as the means ± SD. Student's t test.
‡
Values are expressed as median (p5-p95). Mann-Whitney test. IR: insulin resistance; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; HOMA-IR: homeostasis model of assessment-insulin resistance; hsCRP: high sensitivity C-reactive protein.