Table 3. Association of insulin resistance with genotype and allele frequencies of MCP-1 polymorphism.

Genotype/allele		Group without IR (n = 117) % (n)	Group with IR (n = 57) % (n)	P†	OR crude (95% CI); P	OR adjusted (95% CI); P‡
Frequencies				0.13
	AA*	17 (20)	12 (7)		1
	AG	48 (56)	37 (21)		1.1 (0.4-2.9); 0.89
	GG	35 (41)	51 (29)		2.0 (0.8-5.4); 0.16
Frequencies				0.08
	A*	41 (96)	31 (35)		1
	G	59 (138)	69 (79)		1.6 (1.0-2.6); 0.06
Dominant model				0.41
	AA*	17 (20)	12 (7)		1	1
	AG+GG	83 (97)	88 (50)		1.5 (0.6-3.7); 0.41	1.6 (0.6-4.3); 0.37
Recessive model				0.04
	AA+AG*	65 (76)	49 (28)		1
	GG	35 (41)	51 (29)		1.9 (1.0-3.6); 0.04	2.2 (1.1-4.5); 0.03
Additive model		-	-	-	1.5 (0.96-2.5); 0.07	1.7 (0.98-2.7); 0.05

^*Reference category;

^†Chi square test.

^‡Genetic model adjusted by age, gender, obesity and hypertension.

IR: insulin resistance; OR: odds ratio.