Table 5. Multiple regressive stepwise analysis for oxidative stress evaluation in different components of the metabolic syndrome.
| Parameters | Wald | p | Odds-Ratio | Confidence interval | |
|---|---|---|---|---|---|
| TG | Sex | 8.613 | 0.003 | 0.289 | 0.126 – 0.662 |
| Age | 0.098 | 0.755 | 1.005 | 0.972 – 1.040 | |
| BMI | 21.695 | < 0.0001 | 1.212 | 1.118 – 1.314 | |
| AOPP | 20.380 | < 0.0001 | 1.011 | 1.006 – 1.016 | |
| NO | 1.082 | 0.298 | 0.992 | 0.977 – 1.007 | |
| SH | 0.104 | 0.748 | 1.949 | 0.033 – 113.506 | |
| TRAP-UA | 4.495 | 0.034 | 0.990 | 0.980 – 0.999 | |
| HDL | BMI | 13.434 | < 0.0001 | 1.113 | 1.051 – 1.179 |
| AOPP | 14.431 | < 0.0001 | 1.006 | 1.003 – 1.010 | |
| NO | 5.006 | 0.025 | 0.987 | 0.975 – 0.998 | |
| TRAP-UA | 0.062 | 0.803 | 0.999 | 0.993 – 1.005 | |
| Blood Pressure | Age | 20.787 | < 0.0001 | 1.086 | 1.048 – 1.125 |
| BMI | 16.929 | < 0.0001 | 1.167 | 1.084 – 1.256 | |
| AOPP | 5.683 | 0.017 | 1.005 | 1.001 – 1.009 | |
| NO | 3.509 | 0.061 | 1.013 | 0.999 – 1.028 | |
| SH | 0.737 | 0.391 | 4.993 | 0.127 – 196.458 | |
| TRAP-UA | 1.586 | 0.208 | 0.995 | 0.987 – 1.003 | |
| HOMA-IR | Age | 4.753 | 0.029 | 0.969 | 0.0942 – 0.997 |
| BMI | 57.168 | < 0.0001 | 1.463 | 1.325 – 1.614 | |
| AOPP | 5.092 | 0.024 | 1.004 | 1.001 – 1.008 | |
| NO | 1.574 | 0.210 | 0.991 | 0.977 – 1.005 | |
| TRAP-UA | 0.370 | 0.543 | 0.998 | 0.990 – 1.005 |
TG: triacylglycerol; HDL: high-density lipoprotein; HOMA-IR: homeostasis model assessment-insulin resistance; BMI: body mass index; AOPP: advanced oxidation protein products; NO: nitric oxide; Sulfhydryl (SH) groups of proteins; TRAP-UA: total radical-trapping antioxidant parameter-uric acid.
After adjusting for sex and age AOPP maintained its significance for TG, HDL, hypertension and HOMA-IR, NO maintained its significance for HDL and TRAP-AU maintained its significance for TG. Whereas the other oxidative and nitrosative stress markers lost significance.