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. 2016 Nov 7;61(3):269–275. doi: 10.1590/2359-3997000000223

Table 4. Thyroid volume, echogenicity, and presence of nodules by gender in oldest-old individuals.

  Men Women
Normal TSH Increased TSH P Normal TSH Increased TSH P
  (n = 35) (n = 19)   (n = 17) (n = 10)  
 
Thyroid volume (mL) – Mean ± SD            
Total 11.66 ± 3.40 12.86 ± 4.78   10.13 ± 3.90 8.24 ± 5.68 0.015a
< 6 mL (n; %) 0; 0.0% 0; 0.0%   8; 21.1% 12; 44.4% 0.082c
> 20 mL (n; %) 0; 0.0% 0; 0.0%   0; 0.0% 1;3.7% 0.415b
Echogenicity – (n; %)            
ECO1 10; 71.4% 2; 100.0%   20; 52.6% 5; 18.5% 0.001c
ECO2 1; 7.1% 0; 0.0% 14; 36.8% 9; 33.3%
ECO3 3; 21.4% 0; 0.0% 4; 10.5% 13; 48.1%
Nodules – (n; %)            
Yes 8; 57.1% 1; 50.0%   29; 67.4% 14; 32.6% 0.074c
No 12; 34.3% 12; 63.2%   3; 17.6% 3; 30%  

* Student’s t test; a Mann-Whitney test; b Fisher’s exact test; c Chi-square test.

ECO1: isoechoic (the echogenicity of the parenchyma was similar to that of the submandibular gland); ECO2: mildly hypoechoic (the parenchyma was hypoechoic compared with the submandibular gland, but hyperechoic in relation to the cervical muscles); ECO3: hypoechoic (the parenchyma was isoechoic or hypoechoic when compared with the cervical muscles).