Table 4. Individual characteristics of patients with DTC that developed NSSPM.
| Gender | DTC histological subtype | Age at DTC diagnosis (years) | Age at NSSPM diagnosis (years) | RAI-131 | Cumulative I-131 activity (mCi) | Time period from RAI-131 and NSSPM (years) | NSSPM Histological type | |
|---|---|---|---|---|---|---|---|---|
| 1 | F | FTC | 36.4 | 61.1 | Yes | 100 | 4.3 | Adenocarcinoma# |
| 2 | F | PTC | 42.2 | 69.2 | Yes | 100 | 16.8 | Skin (melanoma) |
| 3 | M | FTC | 68.2 | 78.5 | Yes | 620 | 9.7 | Prostate |
| 4 | F | FTC | 68.1 | 69.8 | Yes | 150 | 1.1 | Breast |
| 5 | F | PTC | 52.5 | 61.5 | Yes | 300 | 8.9 | Uterus |
| 6 | F | PTC | 59.3 | 68.3 | Yes | 100 | 8.1 | Skin (BCC) |
| 7 | F | PTC | 64.8 | 75.0 | Yes | 350 | 9.8 | Breast |
| 8 | F | PTC | 48.6 | 53.9 | Yes | 350 | 4.0 | Gastric |
| 9 | F | PTC | 48.0 | 52.4 | Yes | 100 | 3.7 | Uterus |
| 10 | F | PTC | 76.5 | 79.3 | Yes | 150 | 2.6 | Breast |
| 11 | F | PTC | 59.1 | 72.3 | Yes | 900 | 12.8 | Breast |
| 12 | M | FTC | 53.3 | 55.3 | Yes | 150 | 2.0 | Skin (SCC) |
| 13 | F | PTC | 42.1 | 46.5 | Yes | 100 | 3.8 | Lungs |
| 14 | F | PTC | 39.4 | 41.9 | No | - | - | Breast |
| 15 | F | FTC | 43.3 | 56.7 | No | - | - | Skin (BCC) |
| 16 | M | PTC | 49.1 | 54.1 | No | - | - | Prostate |
| 17 | F | PTC | 39.3 | 44.0 | No | - | - | Breast |
DTC: differentiated thyroid carcinoma; NSSPM: non-synchronous second primary malignancy; RAI-131= I131 radioactive iodine treatment; F: female; M: male; PTC: papillary thyroid carcinoma; FTC: follicular thyroid carcinoma; BCC: basal cell cancer; SCC: squamous cell cancer. # Adenocarcinoma indicates glandular epithelium neoplasm from unknown site other than thyroid cancer, excluded by immunohistochemical study.