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. 2020 Mar 30;64(5):575–583. doi: 10.20945/2359-3997000000223

Table 2. Mean EuroQol five dimensions (EQ-5D) utility values by variables in unadjusted and adjusted analysis.

  Mean (95% CI) p value Adjusted mean* (95% CI) F p value
Sex          
 Female 0.727 (0.695 – 0.760) 0.001 0.572 (0.487 – 0.658) 14475 0.001
 Male 0.824 (0.783 – 0.864)   0.671 (0.581 – 0.759)    
Skin color          
 White 0.753 (0.724 – 0.781) 0.020 0.601 (0.524 – 0.678) 1290 0.258
 2Non-white 0.836 (0.772 – 0.900)   0.641 (0.539 – 0.744)    
DM treatment          
 Diet 0.779 (0.693 – 0.866) 0.283 NA NA NA
 Oral medications 0.778 (0.748 – 0.808)        
 Insulin 0.731 (0.671 – 0.791)        
Controlled DM          
 Yes 0.774 (0.743 – 0.806) 0.359 NA NA NA
 No 0.756 (0.714 – 0.798)        
Controlled hypertension
 Yes 0.756 (0.723 – 0.789) 0.549 NA NA NA
 No 0.774 (0.771 – 0.832)        
Dyslipidemia          
 Yes 0.751 (0.720 – 0.782) 0.123 NA NA NA
 No 0.801 (0.752 – 0.850)        
Macrovascular complications
 Yes 0.687 (0.629 – 0.746) 0.001 0.563 (0.468 – 0.657) 15786 0.001
 No 0.791 (0.764 – 0.819)   0.679 (0.598 – 0.761)    
Microvascular complications
 Yes 0.745 (0.711 – 0.780) 0.060   0.872 0.352
 No 0.804 (0.767 – 0.842)        
Other comorbidities          
 Yes 0.709 (0.653 – 0.765) 0.020 0.608 (0.529 – 0.687) 1757 0.187
 No 0.782 (0.753 – 0.811)   0.634 (0.538 – 0.731)    
Ophthalmic diseases
 Yes 0.714 (0.659 – 0.769) 0.060   2188 0.141
 No 0.777 (0.748 – 0.806)        
DR health states          
 NoDR 0.773 (0.746 – 0.800) 0.001 0.748 (0.698 – 0.798)** 5041 0.002
 Non-STDR 0.801 (0.726 – 0.875)   0.752 (0.679 – 0.825)**    
 STDR 0.658 (0.521 – 0.794)   0.628 (0.521 – 0.736)    
 BB 0.356 (0.061 – 0.651)   0.355 (0.105 – 0.606)**    

SD: standard deviation; NA: not applicable, variables not included in the adjusted analysis; DM: diabetes mellitus; DR: diabetic retinopathy; NoDR: absence of diabetic retinopathy; Non-STDR: non-sight-threatening diabetic retinopathy; STDR: sight-threatening diabetic retinopathy; BB: bilateral blindness. *Analysis adjusted by age, sex, skin color, other comorbidities, macrovascular and microvascular complications, and ophthalmic diseases. R square = 0.242; Adjusted R square = 0.202. **Bonferroni test: NoDR and BB (p = 0.01); Non-STDR and BB (p = 0.01).