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. 2018 Mar 23;62(2):236–263. doi: 10.20945/2359-3997000000032

Table 5. Indications for surgery in prolactinomas.

Increasing tumor size despite optimal medical therapy
Pituitary apoplexy
Intolerance to dopamine agonists
Resistance to dopamine-agonists
Persistent optic chiasm compression
Cerebrospinal fluid leak during administration of dopamine agonists

Adapted from Refs. 6, 10, and 19.