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. 2023 Feb 10;145(5):597–610. doi: 10.1007/s00401-023-02547-3

Table 1.

Summary of mouse lines

Mouse line Type of α-synuclein
TgNg Transgene negative
I2-2 Human wild type α-synuclein
G2-3 High expression levels of human A53T mutant α-synuclein
H5 Low expression levels of human A53T mutant α-synuclein
O2 Human A30P mutant α-synuclein
iSyn Neuronal expression of human A53T mutant α-synuclein
SynKO α-synuclein knockout

Mouse lines used in this study and their expression of α-synuclein