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. 2023 Apr 20;14:2277. doi: 10.1038/s41467-023-38013-7

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© The Author(s) 2023, corrected publication 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Panels: KDM-BA acceleration (a) and PhenoAge acceleration (b). Solid line: Point estimation; Dash line: Confidence limits; Dots: Knots (5th, 50th, and 95th percentiles). Restricted cubic spline regression model adjusted for age, sex, BMI category, race, smoking status (current/former/never), healthy alcohol intake status, healthy physical activity status, Townsend deprivation index, and prevalent hypertension, CHD, and diabetes. Source data are provided as a Source Data file.