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. 2023 Apr 20;14:2131. doi: 10.1038/s41467-023-37838-6

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — a Venn diagram showing the number of genes related to cardiac muscle contraction or dilated cardiomyopathy (DCM) as well as of those with differential ribosome occupancy at Pro/Ala codons or with disome peaks in the heart of Rpl3l^+/+ or Rpl3l^−/− mice (n = 4 mice). b Cumulative fraction for the fold change in protein expression in the heart of Rpl3l^−/− mice compared with that of control mice (n = 4 mice). The expression level of proteins was analyzed by DIA-based MS, and the results are shown for all proteins (n = 3376) and for those encoded by the overlapping genes enclosed by the red boundaries in a (n = 12). The P value was calculated with the two-tailed Mann-Whitney U test. c Venn diagram showing the number of genes for mitochondrial respiratory complex subunits encoded by the nuclear genome as well as of those with differential ribosome occupancy at Pro/Ala codons or with disome peaks in the heart of Rpl3l^+/+ or Rpl3l^−/− mice (n = 4 mice). d Cumulative fraction for the fold change in protein expression in the heart of Rpl3l^−/− mice compared with that of control mice (n = 4 mice). The expression level of proteins was analyzed by DIA-based MS, and the results are shown for all proteins (n = 3376) and for those encoded by the overlapping genes enclosed by the red boundaries in c (n = 35). The P value was calculated with the two-tailed Mann-Whitney U test. Source data are provided as a Source Data file.