Table 1.

Summary of primary research papers identified

First author	Y	Publication	Species	GENET	Iron	DA	OT	STR	SC	PRE	FV	CV
Allen	2020	Sleep Med 71:141–8	Mouse		+	+					+
Ashkenazi	1982	Pharmacol Biochem Behav 17(S1):43–7	Rat		+	+						+
Baier	2002	J Neurol Sci 98:71–7	Rat			+
Barraud	2010	Plos One 5:e13306	Monkey			+			+		NA	NA
Beard	1994	Pharmacol Biochem Behav 48:621–4	Rat		+	+		+				+
Ben-Shachar	1985	J Neurochem 45:999–1005	Rat		+	+		+				+
Berteotti	2021	J Sleep Res 30:e13255	Mouse				H
Bianco	2008	J Neurochem 106:205–15	Rat		+	+		+				+
Bianco	2009	Chronobiol Int 26:447–63	Mouse		+	+		+				+
Carkaci-Salli	2012	J Neurosci Res 90:1583–8	Mouse		+	+
Cathiard	2021	J Sleep Res 30:e13311	Mouse	Meis1		+		+			+	+
Catoire	2011	Ann Neurol 70:170–5	Worm	Meis1	+						NA	NA
Chen	1995	J Nutr 125:1529–35	Rat		+							+
Clemens	2004	J Neurosci 24:11337–45	Mouse			+						+
Clemens	2005	Neuroscience 133:353–7	Mouse			+			+
Connor	2008	J Neurosci Res 86:3194–202	Mouse		+	+		+				+
Dean	2006	Sleep Med 7:634–40	Mouse		+
DeAndrade	2012	Hum Mol Genetics 21:3984–92	Mouse	Btbd9	+	+		+			+	+
DeAndrade	2012	Plos One 7:e35518	Mouse	Btbd9								+
Dinkins	2017	Sleep Med 40:47–52	Mouse			+						+
Dowling	2009	J Nutr 139:2087–92	Mouse		+				+			+
Dowling	2011	J Neurosci 31:70–7	Mouse		+	+						+
Drgonova	2015	Mol Med 21:717–25	Mouse	Ptprd								+
Earley	2020	Sleep Med 71:135–40	Mouse		+	+						+
Erikson	2000	J Nutr 130:2831–7	Rat		+			+				+
Erikson	2001	Physiol Pharmacol Behav 69:409–18	Rat		+	+		+				+
Esteves	2013	J Motor Behav 45:487–93	Rat			+
Esteves	2016	Brain Res 1639:47–57	Rat			+		+
Franco	2021	J Neurosci Res 99:3325–38	Rat		+	+		+
Frank	2016	Physiol Behav 154:161–8	Rat			+		+
Freeman	2012	Curr Biol 22:1142–8	Fly	Btbd9	+	+					NA	NA
Gao	2022	ACS Omega 7:11839–52	Mouse	Btbd9								+
Glover	1972	Br J Med 2:627–8	Rat		+							+
Gulyani	2009	Exp Neurol 215:236–42	Mouse		+		A	+				+
Guo	2017	Sci Rep 7:9905	Rat			+		+	+
Huang	2021	Front Aging Neurosci 13:651638	Mouse	Map2k5		+		+				+
Hunt	1994	Am J Clin Nutr 59:413–8	Rat		+							+
Hyacinthe	2015	Neuroscience 290:621–35	Monkey		+	+		+			NA	NA
Jellen	2013	Neuroscience 252:13–23	Mouse		+	+
Keeler	2012	Exp Neurol 238:273–83	Mouse			+			+			+
Koo	2008	Mov Disord 23:1234–42	Rat								+
Lai	2008	Neuroscience 154:431–43	Cat			+					NA	NA
Lai	2017	Mov Disord 32:1687–93	Rat		+	+		+			+
Lai	2020	Sleep 43:zsz223	Rat		+		H	+			+
Lai	2022	Sleep 45:zsac110	Rat		+	+	H	+			+
Lo Martire	2018	Front Physiol 9:1818	Mouse		+							+
Lopes	2012	Mov Disord 27:413–20	Rat			+			+
Luo	2011	Sleep Med 12:41–6	Mouse		+	+			+
Lyu	2019	Behav Brain Res 374:112123	Mouse		+	+	O	+				+
Lyu	2019	eNeuro 6:ENEURO.0277–19.2019	Mouse	Btbd9				+			+	+
Lyu	2020	Brain Struct Funct 225:1743–60	Worm Mouse	Btbd9 Btbd9		+   +		+			NA	NA  +
Lyu	2020	Exp Neurol 323:113111	Mouse	Btbd9		+		+			+	+
Lyu	2020	J Neurochem 155:522–37	Worm Mouse	Meis1 Meis1	+	+   +		+			NA  +	NA  +
Lyu	2020	J Neurosci Res 98:1532–48	Mouse		+	+	O	+				+
Lyu	2020	Neuroscience 440:85–96	Mouse	Btbd9							+	+
Mariano	2014	Rev Bras Gin Obst 36:436–41	Rat							+		+
Meneely	2018	Front Behav Neurosci 12:199	Mouse	Meis1	+	+	O		+			+
Morais	2021	J Sleep Res 30:e13216	Rat	Ptprd		+		+	+
Muramatsu	2019	Sci Rep 9:16344	Mouse	Btbd9		+						+
Nelson	1997	J Nutr 127:2282–8	Rat		+	+		+				+
Ondo	2000	Mov Disord 15:154–8	Rat			+			+
Pappas	2008	Brain Res 1214:1–10	Mouse			+		+	+
Qu	2006	Exp Brain Res 168:152–6	Mouse			+			+
Quiroz	2010	Exp Neurol 224:292–8	Rat		+		A	+				+
Quiroz	2016	Neuropharmacol 111:160–8	Mouse Rat		+   +	+   +	A A	+   +				+   +
Reis	2011	Spinal Cord 49:361–4	Rat		+				+
Rivera-Oliver	2019	Mol Neurobiol 56:797–811	Mouse			+	H		+
Salminen	2017	Dis Mod Mech 10:981–91	Mouse	Meis1	+	+						+
Salminen	2018	J Sleep Res 27:e12557	Mouse	Meis1		+						+
Schulte	2014	Am J Hum Gen 95:85–95	Fish	Meis1							NA	NA
Silvani	2015	J Sleep Res 24:695–701	Mouse Rat
Spieler	2014	Genome Res 24:592:603	Mouse	Meis1								+
Sun	2011	J Neurol Sci 304:93–101	Rat		+	+	O	+
Unger	2008	J Nutr 138:2487–94	Rat		+	+		+				+
Unger	2009	J Appl Physiol 106:187–93	Mouse		+							+
Unger	2013	Neuroscience 246:179–85	Mouse		+			+				+
Unger	2014	Exp Neurol 261:462–8	Rat		+	+		+				+
Wang	2004	J Neurol Sci 220:59–66	Rat		+
Yepes	2017	Ann Neurol 82:951–60	Rat		+	+	G	+				+
Zhao	2007	J Neurosci Res 85:1065–76	Mouse		+	+			+			+
Zhu	2008	J Comp Physiol A 194:957–62	Mouse			+			+

Y year of publication, GENET genetic factors, DA dopamine, OT other transmitters (A adenosine, H histamine, Glu glutamate, O opioids), STR striatum, SC spinal cord, P pregnancy, FV face validity, CV construct validity, NA not applicable