Table 3.
MRI correlation studies
| Study | MRI measurement technique for ROI | MRI sequence (s) for ROI | DEXA | Max. duration between MRI and DEXA | Patients’ population | Control group | Mean age (years) | Total number of patients | Year of publication | MRI measurements Level | Study design |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Ergen et al. [38] | BMFF (using T2*-IDEAL technique) | T1W spine echo sequence (TR:660 ms, TE: 8.5ms) and STIR sequence (TR: 3500 ms, TE: 42 ms) | Spine DEXA BMD | 3 wk | Female patients with low back pain from single center | NA | 49.3 | 45 | 2014 | L1–4 | prospective |
| Agrawal et al. [37] | BMFF and ADC (using DWI and MR Spectroscopy sequences) | T1W, T2W spine echo sequence | Spine DEXA T score & BMD | 18 mo | Indian postmenopausal women who underwent DEXA in recruited randomly from single center | NA | 52.4 | 50 | 2015 | L3 | prospective |
| Shen et al. [41] | BMAT | T1W whole body MRI | Spine DEXA BMD, hip DEXA BMD | Non specified | African American, Caucasian recruited from CARDIA study | NA | Undefined | 76 | 2012 | L1–5 | prospective |
| Shih et al. [35] | LWR, lipid LW, water LW (using proton MR spectroscopy sequence) | T1W, T2W spine echo sequence | Spine DEXA BMD | 2 wk | Female patients who referred to orthopedic or osteoporosis clinic | NA | 58 | 52 | 2004 | L3 | prospective |
| Saad et al. [42] | M score (calculated from SNR) | T1W spine echo sequence (TR: 400-600 ms, TE:7 ms) | Spine DEXA T score & BMD | 6 mo | Postmenopausal women with low back pain in single center | Healthy female of matched age with normal BMI | 59.4 | 50 | 2019 | L1–4 | retrospective |
| Shayganfar et al. [40] | M score (calculated from SNR) | T1W spine echo sequence (TR:400 ms, TE: 16 ms) | Spine DEXA T score | 6 mo | Iranian postmenopausal women who underwent DEXA in single center | Healthy female aged between 20 and29 y | 59.1 | 82 | 2019 | L1–4 | prospective |
| Shih et al. [36] | Peaked enhanced ratio (BMP) derived from time-Signal intensity curve | T1W spine echo sequence (TR:600 ms, TE: 12 ms) | Spine DEXA BMD | 2 wk | Female patients who referred to orthopedic or osteoporosis clinic | NA | 57 | 62 | 2004 | L1–5 | prospective |
| Bandirali et al. [39] | M score | T1W spine echo sequence (TR: 600 ms, TE: 11 ms) | Spine DEXA T score | 6 mo | Caucasian female patients with low back pain in single center | Healthy Caucasian female aged between 20 and 29 years with normal BMI | 65 | 226 | 2015 | L1–4 | retrospective |
| Ehresman et al. [31] | VBQ score | T1W spine echo sequence | Hip DEXA T score, lowest skeletal T score | 2 y | Patients undergoing degenerative spine surgery in single center | NA | Undefined | 68 | 2019 | L1-4 | retrospective |
| Chang et al. [32] | PD (using synthetic MRI sequences; T1 map, T2 map, PD map) and VBQ score, T1 intensity | T1W spine echo sequence | Spine DEXA T score | 3 mo | Patients undergoing degenerative spine surgery in single center | NA | 61.9 | 62 | 2021 | L1–4 | prospective |