Fig. 5.

Association between the expression of T cells, interferon-γ, and inflammatory signature with partial response or stable disease for ≥16 weeks (A), gene sets at baseline that were associated with partial response or stable disease for ≥16 weeks (B), and gene sets with expression that changed from baseline today 8 ofcycle 2(C)∗. ∗Analyses included the 27 patients in the RNA sequencing subgroup. C2D8 = day 8 of cycle 2; IFN = interferon; IL = interleukin; JAK = Janus kinase; NF = nuclear factor; PR = partial response; SD = stable disease; STAT = signal transducer and activator of transcription; TNF = tumour necrosis factor.