Skip to main content
. 2023 Apr 21;21:272. doi: 10.1186/s12967-023-04107-5

Table 2.

Genetic correlation estimates for IBS and neuroticism, depression and anxiety using Linkage Disequilibrium Score Regression (LDSC)

Trait 1 Trait 2 Genetic Correlation SE Z P-value Intercept (SE) Trait 1 Trait 2
h2 (SE) h2 (SE)
IBS Neuroticism 0.526 0.027 19.298 5.54E-83 1.013 (0.013) 0.069 (0.004) 0.146 (0.005)
IBS Depression 0.587 0.026 22.714 3.23E-114 0.992 (0.01) 0.069 (0.004) 0.099 (0.004)
IBS Anxiety 0.677 0.065 10.360 3.75E-25 0.999 (0.74) 0.068 (0.004) 0.083 (0.011)

SE, standard error; h2 heritability