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. 2023 Apr 20;25:44. doi: 10.1186/s13058-023-01615-6

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — miR-214-5P regulates the expression of RAD51 in TNBC. A Comparison of RAD51 expression in AA (MDAMB468/HCC1806) and EA (MDAMB231/MDAMB453) TNBC cell lines analyzed by RT-PCR in three independent experiments. B Comparison of miR-142-3P expression in AA (MDAMB468/HCC1806) and EA (MDAMB231/MDAMB453) TNBC cell lines analyzed by RT-PCR in three independent experiments. C Comparison of miR-214-5P expression in AA (MDAMB468/HCC1806) and EA (MDAMB231/MDAMB453) TNBC cell lines analyzed by RT-PCR in three independent experiments. D Western blot analysis of RAD51 in MDAMB468 cells transfected with miR-214-5P at time points indicated. E Western blot analysis of RAD51 in MDAMB468 cells transfected with miR-142-3P at time points indicated. F Western blot analysis of RAD51 in TNBC cells transfected with miR-214-5P. G Histogram representation of cell cycle profile in MDAMB468 cells 48 h after transfected with miR-214-5P in three independent experiments. (***p < 0.001) and (****p < 0.0001)