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[Preprint]. 2023 May 2:2023.04.11.536376. Originally published 2023 Apr 12. [Version 2] doi: 10.1101/2023.04.11.536376

PMC10120626.1; 2023 Apr 12
PMC10120626.2; 2023 May 2

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Figure 5. — After 5 days and 12 days of stimulation, daily bouts of optogenetic loading led to significant downregulation of genes associated with tendon stem cell activation and ECM synthesis in tendon and upregulation of proinflammatory markers in bone. Blue indicates genes upregulated with loading compared to naïve and pink indicates genes downregulated with loading compared to naïve. Data shown are log2 fold change (x-axis) and −log10 transformed (y-axis).