Skip to main content
[Preprint]. 2023 Mar 13:2023.03.10.532018. [Version 2] doi: 10.1101/2023.03.10.532018

Figure 6. TBX3 binds the E-box of pigmentation gene targets.

Figure 6.

(A) Intersection showing the number of murine genes (4072) associated with ChIP peaks in both our TBX3 dataset and a published MITF dataset. (B) Intersection of PGS genes identified as targets of both TBX3 and MITF. (C) UCSC browser view of TBX3 and MITF ChIP peaks associated with pigmentation genes. Browser tracks are as follows: TBX3 = replicated binding sites in our dataset; MITF = ChIP peaks from Strub et al; cCRE=encode annotated candidate cis-regulatory elements. The location of verified MITF regulatory elements containing E-box motifs are indicated (*) (refs in text).