Table 2.
Associations Between NPAR and All-Cause Mortality by Cox Analysis
| The Number of Events (Deaths), n (%) | Unadjusted HR (95 CI, P) | Minimally Adjusted, HR (95 CI, P) | Fully Adjusted, HR (95 CI, P) | |
|---|---|---|---|---|
| NPAR | 99 (8.7) | 1.15 (1.13, 1.17) <0.001 | 1.15 (1.12, 1.17) <0.001 | 1.13 (1.09, 1.16) <0.001 |
| NPAR (tertiles) | ||||
| T1 | 3 (0.8) | Ref | Ref | Ref |
| T2 | 18 (4.7) | 6.08 (1.79, 20.64) 0.004 | 5.62 (1.65, 19.08) 0.006 | 4.43 (1.30, 15.18) 0.016 |
| T3 | 78 (20.5) | 28.89 (9.12, 91.52) <0.001 | 24.23 (7.61, 77.12) <0.001 | 13.52 (4.14, 44.21) <0.001 |
| P for trend | -- | <0.001 | <0.001 | <0.001 |
Notes: Minimally adjusted HR controls for age, sex, SBP. Fully adjusted HR controls for age, sex, SBP, AF type, history of cancer, primary reason of hospital admission, LVEF, CRP, total cholesterol, hemoglobin, eGFR, urea, BNP and HAS-BLED score.
Abbreviations: AF, atrial fibrillation; NPAR, neutrophil percentage-to-albumin ratio; SBP, systolic pressure; CRP, C reactive protein; eGFR, estimated glomerular filtration rate; WBC, white blood cell; BNP, brain natriuretic peptide; LVEF, left ventricular ejection fraction.