Skip to main content
. Author manuscript; available in PMC: 2023 Sep 1.
Published in final edited form as: Respir Med. 2022 Aug 3;201:106943. doi: 10.1016/j.rmed.2022.106943

Table 4:

Baseline socio-demographic and clinical characteristics of case-control study participants, stratified by incident RA-ILD case status

Overall Incident ILD Cases Controls P value
N 58 22 36
Age, median (IQR) 65 (60, 69) 65 (64, 70) 65 (59.5, 69) 0.77
Male (%) 54 (93) 20 (91) 34 (94) 0.61
Race (%) White or Caucasian 43 (74) 16 (73) 27 (75) 0.52
Black or African American 10 (17) 5 (23) 5 (14)
Other 5 (9) 1 (5) 4 (11)
Ethnicity (%) Hispanic or Latino 3 (5) 1 (5) 2 (6) 0.84
Not Hispanic or Latino 51 (88) 20 (91) 31 (86)
Missing 4 (7) 1 (5) 3 (8)
BMI, median (IQR) 28.8 (25.0, 31.1) 29.1 (24.6, 31.1) 28.7 (25.7, 31.0) 0.76
Smoking history (%) Never 11 (19) 3 (14) 8 (22) 0.14
Former 11 (19) 7 (32) 4 (11)
Current 36 (62) 12 (55) 24 (67)
Hypertension (%) 6 (10) 3 (8) 3 (14) 0.52
Cardiac disease (%) 1 (2) 1 (3) 0 (0) 0.43
Diabetes mellitus (%) 8 (14) 3 (8) 5 (23) 0.12
COPD or asthma (%) 2 (3) 1 (3) 1 (5) 0.72
RA disease duration, years, median (IQR) 10.5 (1.8, 17.4) 8.0 (1.8, 15.3) 10.8 (3.2, 19.0) 0.30
DAS28, median (IQR) 3.0 (2.3, 4.2) 2.9 (2.4, 3.8) 3.2 (2.2, 4.5) 0.67
MDHAQ, median (IQR) 0.7 (0.4, 1.2) 0.8 (0.4, 1.1) 0.7 (0.4, 1.2) 0.76
Prednisone use (%) 27 (47) 11 (50) 16 (44) 0.68
Methotrexate use (%) 33 (57) 15 (68) 18 (50) 0.17
Anti-TNF use (%) 20 (34) 8 (36) 12 (33) 0.81

Abbreviations: RA-ILD = rheumatoid arthritis-associated interstitial lung disease; IQR = interquartile range; BMI = body mass index; COPD = chronic obstructive pulmonary disease; RA = rheumatoid arthritis; DAS28 = Disease Activity Score in 28 Joints; MDHAQ = Multidimensional Health Assessment Questionnaire; TNF = tumor necrosis factor.