|
Study
|
Country
|
Design
|
Model
|
Protocol for COS
|
Protocol for ET
|
Sample size(cycles)
|
Group
|
Age for AMA
|
Outcomes
|
| Soares 2005 |
Spain |
Retro |
OD |
A long protocol |
HRT with or without GnRH-a |
3089 |
<40y; 40-44y; 45-49y; >49y |
45 |
CPR, IR, MR, obstetric outcomes |
| Moomjy 1999 |
USA |
Retro |
OD |
GnRH-a long protocol |
HRT with or without GnRH-a |
370 |
≤34y; 35-42y;≥ 43y |
42 |
CPR, MR |
| Yaron 1998 |
Israel |
Pros |
OD |
HMG alone or with GnRH-a |
HRT |
1001 |
<30y; 31-40y; >40y |
40 |
CPR, MR, LBR |
| Abdalla 1997 |
UK |
Retro |
OD, 2 recipients from different age group shared oocytes from a donor |
Intranasal Buserelin + HMG |
HRT with or without GnRH-a |
104 |
≤39y; ≥40y |
40 |
CPR, IR, LBR |
| Borini 1996 |
Italy |
Retro |
OD, Recipients of different ages shared oocytes from single donor |
Buserelin/LA+FSH/HMG |
HRT |
114 |
≤39y; 40-49y |
40 |
CPR, IR, MR |
| Cano 1995 |
Spain |
Pros |
OD, Recipients of different ages shared oocytes from same cohort of follicles |
Long protocol with LA+HMG/FSH |
HRT |
90 |
<40y; ≥40y |
40 |
CPR, IR, MR |
| Legro 1995 |
USA |
Retro |
OD |
Long protocol with LA + HMG |
HRT |
307 |
≤42y; >42y |
42 |
Ongoing-PR, MR |
| Rosewaks 1995 |
USA |
/ |
Younger IVF-ET donor to older recipients |
/ |
HRT |
48 |
/ |
/ |
Ongoing-PR, IR |
| Balmaceda1994 |
USA |
Retro |
Donor to recipients with POF or poor responder |
Long protocol with LA + HMG |
HRT |
258<189 fresh and 69 frozen) |
≤30y;31-35y;36-40y;41-45y; 46-53y |
40y |
CPR, IR, MR |
| Check 1994 |
New Jersey |
Retro |
Infertile women undergoing IVF shared 50% oocytes to recipients |
Long protocol with LA +HMG |
HRT |
121 |
<40y; ≥40y |
40y |
CPR, LBR |
| Navot 1994 |
USA |
Pros |
Younger donor to older recipients |
HMG or concomitant menotropins and a GnRH-a |
HRT |
89 |
42.7±0.3 vs. 33.4±0.7 |
/ |
CPR, IR, MR, LBR |
| Sauer 1994 |
USA |
Retro |
Fertile young women donate Oocyte to women with different age |
COH with LA and HMG |
HRT |
300 |
<30y;30-39y;40-49y.50-59y |
40 |
IR, LBR |
| Abdalla 1993 |
UK |
Retro |
Oocyte donation |
Intra-nasal buserelin and HMG |
HRT with or without GnRH-a |
371 |
25-29y;30-34y;35-39y;40-44y;45-49y |
40 |
CPR, MR |
| Flamigni 1993 |
Italy |
Retro |
Oocyte donation |
COH with buserelin/LA+FSH/HMG |
HRT |
141 |
21-35y; 36-40y; 41-49y; 50-61y |
40y |
CPR, IR, MR |
| Meldrum 1993 |
USA |
/ |
Oocyte donation |
COH with LA+HMG |
HRT with or without LA |
52 |
<40y; ≥40y |
40y |
CPR |
| Yaron 1993 |
Israel |
Retro |
Oocyte donation |
HMG |
HRT |
458 |
<40y; ≥40y |
40y |
CPR, MR |
| Navot 1991 |
USA |
Pros |
Oocyte donation |
HMG or concomitant menotropins and GnRH-a |
HRT |
89 |
<35y; >40y |
40y |
CPR, LBR |
| Sauer 1991 |
USA |
Pros |
Oocyte donation |
COH with leuprolide and HMG |
HRT |
22 |
<40y;40-44y |
40y |
CPR, IR, LBR |