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. 2023 Feb 27;15(7):2460–2472. doi: 10.18632/aging.204555

Table 1. Characteristics of included studies.

Study Country Design Model Protocol for COS Protocol for ET Sample size(cycles) Group Age for AMA Outcomes
Soares 2005 Spain Retro OD A long protocol HRT with or without GnRH-a 3089 <40y; 40-44y; 45-49y; >49y 45 CPR, IR, MR, obstetric outcomes
Moomjy 1999 USA Retro OD GnRH-a long protocol HRT with or without GnRH-a 370 ≤34y; 35-42y;≥ 43y 42 CPR, MR
Yaron 1998 Israel Pros OD HMG alone or with GnRH-a HRT 1001 <30y; 31-40y; >40y 40 CPR, MR, LBR
Abdalla 1997 UK Retro OD, 2 recipients from different age group shared oocytes from a donor Intranasal Buserelin + HMG HRT with or without GnRH-a 104 ≤39y; ≥40y 40 CPR, IR, LBR
Borini 1996 Italy Retro OD, Recipients of different ages shared oocytes from single donor Buserelin/LA+FSH/HMG HRT 114 ≤39y; 40-49y 40 CPR, IR, MR
Cano 1995 Spain Pros OD, Recipients of different ages shared oocytes from same cohort of follicles Long protocol with LA+HMG/FSH HRT 90 <40y; ≥40y 40 CPR, IR, MR
Legro 1995 USA Retro OD Long protocol with LA + HMG HRT 307 ≤42y; >42y 42 Ongoing-PR, MR
Rosewaks 1995 USA / Younger IVF-ET donor to older recipients / HRT 48 / / Ongoing-PR, IR
Balmaceda1994 USA Retro Donor to recipients with POF or poor responder Long protocol with LA + HMG HRT 258<189 fresh and 69 frozen) ≤30y;31-35y;36-40y;41-45y; 46-53y 40y CPR, IR, MR
Check 1994 New Jersey Retro Infertile women undergoing IVF shared 50% oocytes to recipients Long protocol with LA +HMG HRT 121 <40y; ≥40y 40y CPR, LBR
Navot 1994 USA Pros Younger donor to older recipients HMG or concomitant menotropins and a GnRH-a HRT 89 42.7±0.3 vs. 33.4±0.7 / CPR, IR, MR, LBR
Sauer 1994 USA Retro Fertile young women donate Oocyte to women with different age COH with LA and HMG HRT 300 <30y;30-39y;40-49y.50-59y 40 IR, LBR
Abdalla 1993 UK Retro Oocyte donation Intra-nasal buserelin and HMG HRT with or without GnRH-a 371 25-29y;30-34y;35-39y;40-44y;45-49y 40 CPR, MR
Flamigni 1993 Italy Retro Oocyte donation COH with buserelin/LA+FSH/HMG HRT 141 21-35y; 36-40y; 41-49y; 50-61y 40y CPR, IR, MR
Meldrum 1993 USA / Oocyte donation COH with LA+HMG HRT with or without LA 52 <40y; ≥40y 40y CPR
Yaron 1993 Israel Retro Oocyte donation HMG HRT 458 <40y; ≥40y 40y CPR, MR
Navot 1991 USA Pros Oocyte donation HMG or concomitant menotropins and GnRH-a HRT 89 <35y; >40y 40y CPR, LBR
Sauer 1991 USA Pros Oocyte donation COH with leuprolide and HMG HRT 22 <40y;40-44y 40y CPR, IR, LBR