Table 4. Diagnostic parameters of hs-cTnT thresholds for inpatient mortality.

Hs-cTnT (ng/L)	Sensitivity	95% CI	Specificity	95% CI	PPV	95% CI	NPV	95% CI	+LR	95% CI	-LR	95% CI
3	100	93–100	5	2–10	28	21–35	100	59–100	1.05	1.0–1.1	0	-
5	100	93–100	13	8–20	30	23–37	100	81–100	1.15	1.1–1.2	0	-
10	94	84–99	39	31–48	36	28–45	95	86–99	1.55	1.3–1.8	0.15	0.05–0.5
14 (Normal)	92	81–98	45	37–54	38	29–47	94	85–98	1.68	1.4–2.0	0.17	0.07–0.5
20	86	74–94	55	46–63	41	32–51	92	84–97	1.92	1.5–2.4	0.25	0.1–0.5
23 (Youden)	84	71–93	61	53–69	44	34–55	91	84–96	2.19	1.7–2.8	0.26	0.1–0.5
25	78	65–89	64	56–72	44	34–55	89	81–94	2.20	1.7–2.9	0.34	0.2–0.6
30	69	54–81	67	59–75	43	32–55	86	78–92	2.09	1.5–2.8	0.47	0.3–0.7
35	65	50–78	68	59–76	42	31–54	84	76–90	2.01	1.5–2.8	0.52	0.4–0.8
40	59	44–72	72	64–79	44	32–56	83	75–89	2.11	1.5–3.0	0.57	0.4–0.8
45	57	42–71	74	66–81	45	32–58	83	75–89	2.21	1.5–3.2	0.58	0.4–0.8
50	45	31–60	79	71–85	43	30–58	80	72–86	2.10	1.4–3.3	0.70	0.5–0.9
55	41	28–56	79	71–85	41	28–56	79	71–85	1.92	1.2–3.0	0.75	0.6–1.0
60	41	28–56	81	74–88	45	30–60	79	72–86	2.22	1.4–3.6	0.72	0.6–0.9

CI: Confidence interval; hs-cTnT: High sensitivity cardiac troponin T; +LR: Positive likelihood ratio; -LR: Negative likelihood ratio; NPV: Negative predictive value; PPV: Positive predictive value. Normal denotes the hs-cTnT threshold derived from the 99^th percentile of healthy individuals widely used in clinical practice for detecting cardiac injury. Youden denotes the optimal threshold based on the receiver operating characteristics curve shown in Fig 3.