Table 5.
Summary of wound complications occurring in patients randomized to receive pazopanib (Regimen A) versus no pazopanib (Regimen B)
| Regimen A (RT + chemotherapy + pazopanib) | Regimen B (RT + chemotherapy) | P-value | |
|---|---|---|---|
| (n=17) | (n=5) | ||
| Wound complication grade | |||
| Grade I | 6 (35.29%) | 0 | 0.3208§ |
| Grade II | 3 (17.65%) | 1 (20.00%) | |
| Grade III (IIIa, IIIb, IIIx) | 8 (47.06%) | 4 (80.00%) | |
| Time from surgery to wound complication occurred | |||
| Median (range) | 38.00 (0–220) | 14 (0–70) | 0.6192¥ |
| Delay in treatment | 14 (82.35%) | 2 (40.00%) | 0.1005§ |
| Removed from protocol therapy | 0 | 0 |
RT = radiation therapy
Fisher Exact test was conducted
Two-sample median test was conducted