TABLE 2. Mpox incidence and JYNNEOS first-dose administration rates, relative measures of racial and ethnic disparity, and vaccination-to-case ratios among adult males,* by race and ethnicity† and month — United States, May 10–December 31, 2022.
| Metric | Overall | May–Jun§ | Jul | Aug | Sep | Oct–Dec |
|---|---|---|---|---|---|---|
|
Mpox case incidence (cases per 100,000 MSM)¶
| ||||||
| AI/AN |
291.2
|
2.8 |
53.7 |
144.3 |
62.3 |
28.3 |
| Asian |
258.5
|
15.2 |
91.4 |
100.8 |
31.6 |
19.8 |
| Black or African American |
1,467.8
|
31.5 |
432.4 |
608.8 |
265.4 |
137.4 |
| NH/OPI |
728.6
|
43.5 |
163.2 |
348.7 |
142.2 |
32.9 |
| White |
252.7
|
16.3 |
89.8 |
88.4 |
37.3 |
21.1 |
| Hispanic or Latino |
907.9
|
36.5 |
286.5 |
364.9 |
146.9 |
76.0 |
| Multiple races or other |
968.6
|
28.1 |
318.5 |
350.1 |
168.3 |
107.1 |
|
JYNNEOS vaccine first dose** administration rates (doses administered per 100,000 MSM)¶
| ||||||
| AI/AN |
7,486.6
|
33.9 |
939.0 |
3,283.3 |
2,019.1 |
1,416.0 |
| Asian |
15,315.3
|
60.9 |
2,980.5 |
7,985.0 |
3,198.3 |
1,945.3 |
| Black or African American |
12,920.1
|
25.5 |
1,795.3 |
7,313.1 |
2,673.9 |
1,678.4 |
| NH/OPI |
17,725.1
|
87.0 |
3,003.9 |
9,403.1 |
3,839.5 |
2,550.2 |
| White |
10,735.4
|
65.2 |
2,046.0 |
5,433.1 |
2,213.5 |
1,389.8 |
| Hispanic or Latino |
14,723.5
|
47.6 |
2,533.9 |
7,651.2 |
3,147.3 |
2,132.4 |
| Multiple races or other |
47,188.7
|
189.1 |
7,120.7 |
25,432.9 |
14,545.1 |
10,598.3 |
|
Relative disparities in mpox incidence¶
| ||||||
| Black or African American:White RR |
5.8
|
1.9 |
4.8 |
6.9 |
7.1 |
6.5 |
| Hispanic or Latino:White RR |
3.6
|
2.2 |
3.2 |
4.1 |
3.9 |
3.6 |
|
Relative disparities in JYNNEOS first-dose** vaccination rates¶
| ||||||
| Black or African American:White RR |
1.2
|
0.4 |
0.9 |
1.3 |
1.2 |
1.2 |
| Hispanic or Latino:White RR |
1.4
|
0.7 |
1.2 |
1.4 |
1.4 |
1.5 |
|
Vaccination-to-case ratio††
| ||||||
| AI/AN |
25.7
|
12.0 |
17.5 |
22.5 |
31.1 |
47.0 |
| Asian |
59.2
|
4.0 |
32.6 |
76.9 |
90.6 |
85.2 |
| Black or African American |
8.8
|
0.8 |
4.2 |
11.8 |
9.3 |
11.0 |
| NH/OPI |
24.3
|
2.0 |
18.4 |
26.2 |
23.8 |
66.0 |
| White |
42.5
|
4.0 |
22.8 |
60.2 |
55 |
59.7 |
| Hispanic or Latino |
16.2
|
1.3 |
8.8 |
20.5 |
19.4 |
24.6 |
| Multiple races or other |
48.7
|
6.7 |
22.3 |
67.6 |
60.2 |
59.0 |
| Overall (aggregated measure) | 23.8 | 2.7 | 13.2 | 31.0 | 28.2 | 32.8 |
Abbreviations: AI/AN = American Indian or Alaska Native; mpox = monkeypox; MSM = gay, bisexual, and other men who have sex with men; NH/OPI = Native Hawaiian or other Pacific Islander; RR = rate ratio.
* For incidence and vaccination rates, the numerators were the numbers of cases and first-dose vaccinations, respectively, among all adult males and were not limited to MSM. To obtain meaningful rates, and because MSM were disproportionately affected by the outbreak, the denominators included only MSM, (i.e., incidence and vaccination rates were calculated as cases and vaccinations in all adult males, respectively, per 100,000 MSM). Case data updated through January 8, 2023, at 2:00 p.m. Eastern Time. Vaccination data updated through January 10, 2023.
† All persons who reported Hispanic or Latino (Hispanic) ethnicity, regardless of race, were categorized as Hispanic. Persons who did not report ethnicity as Hispanic (including missing ethnicity) were categorized as non-Hispanic and self-reported race in the following categories: AI/AN, Asian, Black or African American (Black), NH/OPI, White, and multiple races (more than one race category selected) or other race. Persons with missing data on ethnicity and race were categorized as missing or unknown.
§ The first mpox case reporting period in this analysis is May 10–June 30. The first date of JYNNEOS vaccination is May 22, 2022. May–June and October–December were combined into single periods because vaccination and case counts were low during those months.
¶ Denominators for incidence and vaccine administration rates were MSM aged ≥18 years: CDC Wonder 2021 estimates for males aged ≥18 years were multiplied by 3.9% to calculate MSM by race and ethnicity, resulting in the following: Black = 584,332; Hispanic = 908,470; White = 3,083,431; Asian = 288,985; AI/AN = 35,370; NH/OPI = 9,196; and multiple races or other race = 81,973. The number of cases in each period was subtracted from the denominator for the following period. For vaccination administration rates, the number of adult males who were vaccinated in each period was subtracted from the denominator for the following period.
** At least 1 dose administered; includes those with 1 or 2 doses administered.
†† The number of adult males vaccinated within a racial and ethnic group in a period divided by the number of cases in that racial and ethnic group during the same period.