Table II.
PGT-M |
PGT-SR |
PGT-A |
PGT-M/SR + PGT-A |
Total |
||||||
---|---|---|---|---|---|---|---|---|---|---|
# analyses | 1388 | 27% | 462 | 9% | 3003 | 58% | 338 | 7% | 5191 | |
# analyses without transfer* | 409 | 29% | 194 | 42% | 1515 | 50% | 131 | 39% | 2249 | 43% |
# analyses with transfer* | 979 | 71% | 268 | 58% | 1488 | 50% | 207 | 61% | 2942 | 57% |
# transfers | 1375 | 100% | 326 | 100% | 1862 | 0 | 260 | 100% | 3823 | 100% |
# with fresh embryos | 488 | 36% | 130 | 40% | 17 | 1% | 3 | 1% | 638 | 17% |
# with thawed/warmed embryos | 884 | 64% | 196 | 60% | 1845 | 99% | 256 | 98% | 3181 | 83% |
# with fresh and thawed/warmed embryos | 3 | 0% | 0 | 0% | 0 | 0% | 0 | 0% | 3 | 0% |
# not reported | 0 | 0% | 0 | 0% | 0 | 0% | 1 | 0% | 1 | 0% |
# SET | 1260 | 92% | 295 | 90% | 1741 | 94% | 250 | 96% | 3546 | 93% |
# DET | 109 | 8% | 31 | 10% | 121 | 6% | 10 | 4% | 271 | 7% |
# >DET | 6 | 0% | 0 | 0% | 0 | 0% | 0 | 0% | 6 | 0% |
# SET_unknown | 0 | 0% | 0 | 0% | 0 | 0% | 0 | 0% | 0 | 0% |
# positive hCG test | 561 | 41% | 114 | 35% | 1145 | 61% | 151 | 58% | 1971 | 52% |
# lost to FU after positive hCG test | 5 | 0% | 6 | 2% | 15 | 1% | 4 | 2% | 30 | 1% |
# PUL | 86 | 6% | 15 | 5% | 73 | 4% | 9 | 3% | 183 | 5% |
# blighted ovum | 29 | 2% | 5 | 2% | 37 | 2% | 4 | 2% | 75 | 2% |
# ectopic pregnancies | 5 | 0% | 1 | 0% | 4 | 0% | 0 | 0% | 10 | 0% |
# clinical pregnancies | 436 | 32% | 87 | 27% | 1016 | 55% | 134 | 52% | 1673 | 44% |
# lost to FU after clinical pregnancy | 76 | 6% | 15 | 5% | 155 | 8% | 20 | 8% | 266 | 7% |
# pregnancy loss <12 weeks | 19 | 1% | 0 | 0% | 41 | 2% | 5 | 2% | 65 | 2% |
# ongoing pregnancy (>12 weeks) | 341 | 25% | 72 | 22% | 820 | 44% | 109 | 42% | 1342 | 35% |
# singletons | 327 | 24% | 69 | 21% | 786 | 42% | 103 | 40% | 1285 | 34% |
# multiples | 14 | 1% | 3 | 1% | 34 | 2% | 6 | 2% | 57 | 1% |
# lost to FU after ongoing pregnancy | 0 | 0% | 0 | 0% | 1 | 0% | 0 | 0% | 1 | 0% |
# pregnancy loss 12–20 weeks | 6 | 0% | 0 | 0% | 20 | 1% | 2 | 1% | 28 | 1% |
# pregnancy with no live birth | 1 | 0% | 0 | 0% | 5 | 0% | 0 | 0% | 6 | 0% |
# pregnancy with at least one live birth | 334 | 24% | 72 | 22% | 794 | 43% | 107 | 41% | 1307 | 34% |
# live born children | 352 | 77 | 838 | 113 | 1380 |
*% expressed per # analyses
SET: single embryo transfer; DET: double embryo transfer; PUL: pregnancy of unknown location; FU: follow-up; PGT-M: preimplantation genetic testing for monogenic/single gene defects; PGT-SR: PGT for chromosomal structural rearrangements; PGT-A: PGT for aneuploidies; PGT-M/SR + PGT-A: concurrent PGT-M/SR with PGT-A.