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. 2023 Mar 24;26(4):106495. doi: 10.1016/j.isci.2023.106495

Figure 4.

Figure 4

chemerin knockout increased pro-inflammatory cytokines in the heart of HFD mice

Rarres2−/− and Littermate WT mice were subjected to high-fat diet feeding for 20 weeks.

(A) Serum chemerin level was detected by ELISA in both Rarres2−/− and Littermate mice, n = 6.

(B) The RT-qPCR analysis of pro-inflammatory cytokines in the heart between Rarres2−/− and littermate WT mice, n = 3.

(C) Western blots and its quantification of p-P38, P38, and p-P65, P65 in the heart. The HSP90 was used as a loading control (n = 6). ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.