Heatmap of Bonferroni corrected p-values for one-way Wilcoxon-signed rank tests between various registration methods and no registration (None) indicating significant improvement across evaluation metrics and structures. Blue colors correspond to significant p-values (p<0.05) while red colors correspond to non-significant values (p>0.05). Glnd_Submand, submandibular gland; L, left; R, right; GTV_PT, primary gross tumor volume; DSC, Dice similarity coefficient; MSD, mean surface distance.