Table 1:
Demographic and Clinical Characteristics by Oxygen Amount at Initial Discharge
| Mean ± S.D. [Range] | Entire Study Population (n=417) | ≤0.125 LPM (n=149) | >0.125 and <0.5 LPM (n=130) | ≥0.5 and <1.0 LPM (n=111) | ≥1.0 LPM (n=27) | P value | |
|---|---|---|---|---|---|---|---|
| Sex (% male) | 55.6% | 55.7% | 53.9% | 63.1% | 33.3% | 0.044 | |
| Race (% non-white; n=404) | 59.7% | 59.5% | 66.4% | 54.3% | 50.0% | 0.20 | |
| Ethnicity (% Hispanic; n=415) | 5.5% | 5.4% | 4.6% | 4.6% | 14.8% | 0.18 | |
| Gestational age (weeks) | 26.4 ± 2.6 [22.9, 36.9] | 26.3 ± 2.4 [22.9, 36.9] | 26.5 ± 2.7 [23.0, 35.5] | 26.2 ± 2.4 [23.0, 35.3] | 26.8 ± 2.6 [23.4, 36.0] | 0.69 | |
| Birthweight (grams; n=409) | 858 ± 408 [380, 3370] | 868 ± 399 [380, 3370] | 875 ± 455 [390, 3181] | 829 ± 302 [415, 1790] | 836 ± 590 [420, 2790] | 0.82 | |
| Birthweight percentile (%; n=409) | 40 ± 26 [1, 95] | 42 ± 27 [1, 95] | 39 ± 24 [1, 89] | 42 ± 26 [1, 89] | 25 ± 19 [2, 67] | 0.018 | |
| Small for gestational age (% < 10th percentile; n=409) | 13.7% | 13.2% | 13.1% | 12.7% | 24.0% | 0.49 | |
| BPD severity (%; n=387) | Mild | 0.5% | 1.4% | 0.0% | 0.0% | 0.0% | <0.001 |
| Moderate | 34.4% | 47.5% | 38.8% | 17.8% | 7.7% | ||
| Severe | 65.1% | 51.1% | 61.2% | 82.2% | 92.3% | ||
| Gastrostomy tube (% yes) | 33.1% | 16.8% | 33.1% | 46.9% | 66.7% | <0.001 | |
| Nissen fundoplication in subjects with gastrostomies (% yes; n =138) | 65.2% | 52.0% | 60.5% | 71.2% | 77.8% | 0.22 | |
| Pulmonary hypertension after 36 weeks (% yes) | 27.8% | 16.1% | 24.6% | 40.5% | 55.6% | <0.001 | |
| Pulmonary hypertension medications in subjects with pulmonary hypertension (% yes; n=116) | 40.5% | 16.7% | 25.0% | 53.3% | 73.3% | <0.001 | |
| Diuretics (% yes) | 65.5% | 54.4% | 70.0% | 73.0% | 74.1% | 0.005 | |
| Inhaled corticosteroids (% yes) | 74.8% | 65.8% | 77.7% | 79.3% | 92.6% | 0.005 | |
| Initial discharge age (months; n=416) | 4.7 ± 2.5 [0.1, 17.9] | 4.0 ± 2.1 [0.5, 15.3] | 4.7 ± 2.3 [0.1, 14.9] | 5.3 ± 2.8 [1.0, 17.9] | 5.8 ± 3.2 [0.2, 13.6] | <0.001 | |
| Initial discharge age (weeks post-menstrual age; n=416) | 46.7 ± 10.5 [34.7, 105.1] | 43.6 ± 9.1 [34.7, 98.4] | 46.9 ± 9.6 [35.4, 93.0] | 49.4 ± 11.6 [36.3, 105.1] | 52.0 ± 12.6 [35.9, 87.0] | <0.001 | |
| Median household income ($ in thousands; n=413) | 77.2 ± 27.9 [20.4, 156.8] | 81.1 ± 27.8 [28.5, 156.8] | 72.4 ± 26.7 [22.8, 156.8] | 76.1 ± 28.6 [20.4, 145.8] | 83.5 ± 28.9 [31.9, 148.9] | 0.042 | |
| Public insurance (% yes) | 53.2% | 48.3% | 53.1% | 55.9% | 70.4% | 0.18 | |