Table 2:
Likelihood of weaning oxygen in a given month by demographic data clinical characteristics
Hazard Ratio (Univariate Model)* | P value | Hazard Ratio (Multivariate Model)** | P value | ||
---|---|---|---|---|---|
Amount of oxygen at initial discharge (LPM) | 0.26 | <0.001 | 0.41 | <0.001 | |
Sex (male=0; female=1) | 0.95 | 0.64 | - | - | |
Race (white=0; nonwhite=1) | 1.21 | 0.09 | - | - | |
Ethnicity (non-Hispanic=0; Hispanic=1) | 0.94 | 0.80 | - | - | |
Gestational age (months) | 1.01 | 0.52 | - | - | |
Birthweight (grams) | 1.00 | 0.99 | - | - | |
Birthweight percentile (%) | 1.00 | 0.31 | - | - | |
Small for gestational age (no=0; yes=1) | 0.95 | 0.76 | - | - | |
BPD severity (Reference=Mild) | Moderate | 1.84 | 0.56 | - | - |
Severe | 1.21 | 0.85 | - | - | |
Gastrostomy tube (no=0; yes=1) | 0.38 | <0.001 | 0.57 | <0.001 | |
Nissen fundoplication (no=0; yes=1) | 0.39 | <0.001 | - | - | |
Pulmonary hypertension after 36 weeks (no=0; yes=1) | 0.57 | <0.001 | - | - | |
Pulmonary anti-hypertensive medications (no=0; yes=1) | 0.45 | <0.001 | - | - | |
Diuretics (no=0; yes=1) | 0.81 | 0.06 | - | - | |
Inhaled corticosteroids (no=0; yes=1) | 0.31 | <0.001 | 0.39 | <0.001 | |
Discharge age (months) | 0.85 | <0.001 | 0.94 | 0.016 | |
Median household income ($, in thousands) | 1.00 | 0.019 | 1.01 | 0.001 | |
Public insurance (no=0; yes=1) | 0.78 | 0.023 | - | - |
Hazard ratios were generated through Cox regression and adjusted for inter-site variation with a dummy variable.
Model was generated via backwards stepwise regression using variables significant in univariate modeling also with adjustment for site; final model n=412.