Table 1.
Participant Clinical and Demographic Characteristics & Tracer Doses.
| Suicide Attempters (n=13) | Suicide Nonattempters (n=12) | p-value | |
|---|---|---|---|
| Age (years) | 30.0 ± 7.4 | 35.0 ± 10.0 | 0.10 |
| % Female | 69.2% | 33.3% | 0.11 |
| 7.7% Unknown/not reported | |||
| Total Education (years) * | 15.8 ± 2.0 | 15.3 ± 2.0 | 0.54 |
| HDRS-17 | 17.5 ± 5.6 | 17.9 ± 2.9 | 0.83 |
| BDI ** | 25.0 ± 9.0 | 27.3 ± 7.7 | 0.52 |
| BHS ** | 10.8 ± 5.8 | 13.6 ± 5.1 | 0.22 |
| [ 11 C]DASB Injected Dose (mCi) | 13.0 ± 4.9 | 11.4 ± 5.3 | 0.44 |
| [ 11 C]CUMI-101 Injected Dose (mCi) | 12.1 ± 3.9 | 10.8 ± 3.8 | 0.41 |
| [ 11 C]DASB Injected Mass (μg) | 2.0 ± 1.2 | 3.0 ± 1.1 | 0.05 |
| [ 11 C]CUMI-101 Injected Mass (μg) | 2.0 ± 1.1 | 1.7 ± 0.7 | 0.43 |
| EMA stress (proportion of prompts over one week with negative stressor endorsed) | 56.1 ± 25.1% | 55.5 ± 33.0% | 0.96 |
| Days between EMA start and PET scan (EMA – PET) | −6.6 ± 16.1 | −1.7 ± 15.5 | 0.44 |
| Childhood Trauma Questionnaire (CTQ) Total Score + | 51.8 ± 20.7 | 45.1 ± 18.9 | 0.43 |
| SSI Prior Total ++ | 8.4 ± 11.2 | 3.1 ± 3.5 | 0.26 |
| Number of prior suicide attempts +++ | 1.8 ± 1.2 | 0 ± 0 | N/A |
| Suicide attempt recency (years) ++++ | 7.6 ± 7.7 | N/A | N/A |
Abbreviations: HDRS-17 = 17-item Hamilton Depression Rating Scale, mCi = milliCuries.
*
Total education data missing from one nonattempter participant.
**
BDI and BHS missing from one attempter participant.
+
CTQ missing from one attempter and one nonattempter participant
++
SSI Prior Total missing from 6 attempter participants.
+++
Number of prior suicide attempts missing from 1 attempter participant.
++++
Suicide attempt recency missing from 4 attempter participants.