Table 2.

Effect of EMA stress by region for 5-HTT and 5-HT_1A in suicide attempters and nonattempters.

Suicide Attempters: Effect of EMA stress by region
	5-HTT BPND		5-HT1A BPND
	p=0.04*		p=0.005**
	Standardized Beta (β) Estimate [95% CI]	p-value	Standardized Beta (β) Estimate [95% CI]	p-value
Region 1	−0.05 [−0.62, 0.53]	0.87	0.33 [0.10, 0.55]	0.007*
Region 2	−0.37 [−0.94, 0.21]	0.20	0.38 [0.15, 0.61]	0.003**
Region 3	−0.29 [−0.86, 0.29]	0.31	0.36 [0.13, 0.58]	0.004**
Region 4	−0.13 [−0.71, 0.44]	0.63	0.34 [0.12, 0.57]	0.005**
Region 5	−0.49 [−1.07, 0.08]	0.09	0.17 [−0.05, 0.40]	0.13
Region 6	−0.16 [−0.73, 0.42]	0.58	0.33 [0.10, 0.55]	0.007*
Region 7	−0.30 [−0.88, 0.27]	0.28	0.45 [0.23, 0.68]	0.0005**
Region 8	−0.20 [−0.78, 0.37]	0.47	0.35 [0.12, 0.57]	0.005**
Region 9	0.18 [−0.40, 0.75]	0.52	0.36 [0.13, 0.59]	0.004**
Region 10	0.09 [−0.49, 0.66]	0.75	0.41 [0.18, 0.63]	0.001**
Suicide Nonattempters: Effect of EMA stress by region
	5-HTT BPND		5-HT1A BPND
	p=0.015*		p=0.95
	Standardized Beta (β) Estimate [95% CI]	p-value	Standardized Beta (β) Estimate [95% CI]	p-value
Region 1	−0.11 [−0.36, 0.14]	0.33	−0.081 [−0.29, 0.13]	0.42
Region 2	0.06 [−0.29, 0.31]	0.64	−0.051 [−0.26, 0.16]	0.61
Region 3	−0.05 [−0.30, 0.20]	0.65	−0.11 [−0.33, 0.10]	0.26
Region 4	−0.12 [−0.37, 0.13]	0.31	−0.068 [−0.28, 0.14]	0.50
Region 5	−0.07 [−0.33, 0.18]	0.53	−0.076 [−0.29, 0.14]	0.45
Region 6	−0.04 [−0.22, 0.29]	0.77	−0.058 [−0.27, 0.15]	0.56
Region 7	−0.03 [−0.29, 0.22]	0.77	−0.044 [−0.26, 0.17]	0.66
Region 8	−0.03 [−0.28, 0.22]	0.82	−0.074 [−0.29, 0.14]	0.46
Region 9	−0.07 [−0.32, 0.18]	0.54	−0.070 [−0.28, 0.14]	0.49
Region 10	−0.14 [−0.39, 0.12]	0.26	−0.047 [−0.26, 0.16]	0.64

Abbreviations: CI = confidence interval, 5-HTT = serotonin transporter, 5-HT_1A = serotonin receptor 1A, BP_ND = binding potential of interest.

^*p<0.05,

^**survives Bonferroni correction thresholds: p<0.008 for LME model effects of EMA stress by region and p<0.005 for the post-hoc follow-ups in the 10 NRU 5-HT atlas regions