Table 2.

Differences in the MRI parameters between patients in the GBM and atypical PCNSL groups (mean ± SD).

Parameters	GBM group (n = 108)	Atypical PCNSL group (n = 54)	P
ADCmin ( × 10−3 mm2/s)	0.77 ± 0.07	0.68 ± 0.10	< 0.001
ADCmean ( × 10−3 mm2/s)	0.91 ± 0.08	0.80 ± 0.08	< 0.001
ADCmax ( × 10−3 mm2/s)	1.23 ± 0.16	1.19 ± 0.10	0.208
rADC	1.32 ± 0.19	1.13 ± 0.12	< 0.001
rCBVmin	2.38 ± 0.62	2.17 ± 0.67	0.101
rCBVmean	4.03 ± 1.07	2.69 ± 0.81	< 0.001
rCBVmax	7.31 ± 2.29	4.24 ± 0.80	< 0.001
FA	0.19 ± 0.03	0.16 ± 0.02	< 0.001
DA	1.24 ± 0.22	0.98 ± 0.18	< 0.001
DR	0.98 ± 0.11	0.83 ± 0.10	< 0.001
Cho/NAA	2.17 ± 0.80	2.06 ± 0.70	0.441
Cho/Cr	1.03 ± 0.17	1.34 ± 0.29	< 0.001
NAA/Cr	1.09 ± 0.23	1.15 ± 0.27	0.111
Lip/Cr	4.03 ± 0.9	5.48 ± 1.27	< 0.001
Lac/Cr	1.29 ± 0.65	1.40 ± 0.55	0.203

Abbreviations: GBM, glioblastoma; atypical PCNSL, atypical primary central nervous system lymphoma; ADC_min, minimum apparent diffusion coefficient values; ADC_max, maximum ADC values; rADC, relative ADC; rCBV_mean, mean relative cerebral blood volume; rCBV_max, maximum relative cerebral blood volume; FA, fractional anisotropy; DA, axial diffusion coefficient; DR, radial diffusion coefficient; Cho, choline; Cr, creatine; Lip, lipids; DWI, diffusion-weighted imaging; DSC, dynamic susceptibility contrast enhancement; DTI, diffusion tensor imaging; MRS, magnetic resonance spectroscopy.