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. 2023 Apr 10;9(4):e15150. doi: 10.1016/j.heliyon.2023.e15150

Table 3.

Diagnostic performance for discriminating GBM from atypical PCNSL based on different models.

Models AUC (95% CI) Sensitivity (%) Specificity (%) Cutoff
ADCmin ( × 10−3 mm2/s) 0.746 (0.672 to 0.811) 91.6 53.7 >0.692
ADCmean ( × 10−3 mm2/s) 0.826 (0.759 to 0.881) 63.8 88.8 >0.871
rADC 0.792 (0.721 to 0.851) 89.8 59.3 >1.136
rCBVmean 0.862 (0.799 to 0.911) 98.1 59.2 >2.719
rCBVmax 0.905 (0.849 to 0.946) 67.5 98.1 >5.830
FA 0.817 (0.749 to 0.874) 53.7 98.1 >0.188
DA 0.815 (0.746 to 0.871) 97.2 46.3 >0.911
DR 0.820 (0.752 to 0.876) 70.3 75.9 >0.902
Cho/Cr 0.811 (0.742 to 0.868) 94.4 64.8 ≤1.287
Lip/Cr 0.799 (0.729 to 0.858) 57.4 90.7 >4.950
DWI 0.900 (0.843 to 0.941) 64.8 98.1 /
DSC 0.931 (0.881 to 0.965) 93.5 75.9 /
DTI 0.958 (0.914 to 0.983) 86.1 92.5 /
MRS 0.884 (0.825 to 0.929) 65.7 94.4 /
DWI + DSC 0.975 (0.938 to 0.993) 93.5 94.4 /
DWI + DTI 0.980 (0.944 to 0.995) 93.5 94.4 /
DWI + MRS 0.974 (0.936 to 0.993) 89.8 94.4 /
DSC + DTI 0.992 (0.962 to 1.000) 93.5 98.1 /
DSC + MRS 0.984 (0.951 to 0.997) 96.3 92.5 /
DTI + MRS 0.985 (0.952 to 0.998) 94.4 92.5 /

Abbreviations: AUC, area under the curve; 95% CI, 95% confidence interval.

Notes: DWI includes the parameters ADCmin, ADCmean, and rADC; DSC comprises the metrics rCBVmean and rCBVmax; DTI includes FA, DA and DR; MRS comprises the ratios Cho/Cr and Lip/Cr.