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. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: J Immunol. 2023 May 1;210(9):1372–1385. doi: 10.4049/jimmunol.2200900

Figure 1. Sublethal endotoxemia induces hepatic expression of APR factors.

Figure 1.

Fold change in hepatic mRNA expression of (A) Crp, (B) Saa-1, (C) Apcs, (D) Fga (E) Hp and (F) Lbp in endotoxemic (LPS 5 mg/kg, IP; 1 and 5 hours) male and female mice. Data expressed as mean ± SEM (N = 5–7 per sex per exposure). Results of 2way ANOVA for interaction, sex and time provided. Results of multiple comparisons given, with *p<.05 vs. unexposed sex- matched control. †p<.05 vs. time-matched similarly exposed male. (G) Representative Western blot of CRP on whole liver lysate isolated from endotoxemic (LPS 5 mg/kg, IP; 1 and 5 hours) male and female mice. Total protein stain as loading control. (H) Densitometric analysis of whole liver lysate CRP. Data normalized to total protein and expressed as mean ± SEM (N = 4–6 per sex per exposure). *p < 0.05 vs. unexposed control. h = hours.