. 2023 Apr 8;9(4):e15308. doi: 10.1016/j.heliyon.2023.e15308

Table 8.

Evaluating and comparing the selectivity index (SI) of ZnAl-LDH carriers along with amphotericin B (Amp-ZnAl-LDH) and amphotericin B (Amp B) as a positive control drug using IC₅₀ values of samples against amastigote forms of L. major and CC₅₀ values of the drugs on macrophage cell line.

Drugs	Amastigote	Promastigote	Macrophage	selectivity index
Drugs	IC₅₀ (μg/ml)	IC₅₀ (μg/ml)	CC₅₀ (μg/ml)	CC₅₀/IC₅₀_{(value of amastigote forms)}
Amp-ZnAl-LDH	21.05 ± 1.14	111.14 ± 8.28	156.84 ± 2.85	7.45
Amphotericin B	25.41 ± 0.90	65.36 ± 10.86	87.27 ± 1.78	3.43