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. 2023 Mar 21;10(4):ofad154. doi: 10.1093/ofid/ofad154

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© The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Comparison of neutralization against authentic severe acute respiratory syndrome coronavirus 2 Omicron subvariants after infection with BA.2 or BA.2.12.1. (A–D) The geometric mean NT50s are shown and were calculated from at least 2 independent experiments with 2 biological replicates. (A and B) the NT50s for each individual are connected with a line. The factor of difference between subvariants for each individual was calculated and the average indicated. (C) BA.5 NT50 in untreated and nirmatrelvir/ritonavir (NM/r) treated individuals with median indicated (D) BA.2.12.1 NT50s in a single NM/r treated individual over time. Preinfection (Pre) or postinfection, day 11 or 25 postsymptom onset (PSO), NT50s are shown. (E) Graphical abstract of subvariant cross-protection or escape after infection.