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. Author manuscript; available in PMC: 2023 Apr 22.
Published in final edited form as: Eur J Clin Nutr. 2019 Jul 11;74(1):112–125. doi: 10.1038/s41430-019-0464-3

Table 4A.

Associations between maternal serum ferritin concentrations at enrolment and pregnancy and infant outcomes

Model 1b Model 2c


Variablesa n β (SE) or RR (95%CI) P-value n β (SE) or RR (95%CI) P-value
Pregnancy outcomes
 Birth weight, g 244 34.0 (30.5) 0.26 242 31.6 (30.1) 0.29
  Low birth weight (<2500 g), n (%) 244 0.97 (0.70, 1.33) 0.83 242 0.96 (0.70, 1.32) 0.80
 Gestational age at birth, weeks 250 0.14 (0.14) 0.32 248 0.17 (0.14) 0.22
  Preterm (<37 weeks), n (%) 250 0.80 (0.57, 1.13) 0.21 248 0.77 (0.55, 1.09) 0.14
 Preterm and low birth weight, n (%) 244 1.06 (0.63, 1.77) 0.83 242 1.02 (0.61, 1.71) 0.93
 Small for gestational aged, n (%) 243 0.94 (0.77, 1.14) 0.54 241 0.93 (0.76, 1.14) 0.49
Infant outcomes
 Haemoglobin, g/dl 68 0.18 (0.23) 0.42 68 0.25 (0.23) 0.28
  Anaemia (<11.0 g/dl), n (%) 68 0.81 (0.61, 1.07) 0.13 68 0.82 (0.63, 1.08) 0.17
 Length, cm 219 0.46 (0.20) 0.02 217 0.44 (0.20) 0.03
 Length-for-age z-score (LAZ) 217 0.19 (0.10) 0.048 215 0.16 (0.10) 0.09
  LAZ < −2 217 0.83 (0.67, 1.03) 0.09 215 0.86 (0.69, 1.08) 0.20
 Weight-for-age z-score (WAZ) 243 0.07 (0.07) 0.35 241 0.06 (0.07) 0.36
  WAZ < −2 243 0.92 (0.64, 1.33) 0.66 241 0.90 (0.63, 1.30) 0.58
 Weight-for-length z-score (WLZ) 179 −0.10 (0.14) 0.46 177 −0.11 (0.14) 0.44
  WLZ < −2 179 1.00 (0.69, 1.43) 0.98 177 1.03 (0.70, 1.50) 0.90
 BMI z-score (BMIZ) 216 −0.13 (0.11) 0.25 214 −0.13 (0.11) 0.23
  BMIZ < −2 216 1.05 (0.76, 1.44) 0.77 214 1.07 (0.78, 1.47) 0.68
 Ponderal Index, g/cm3 218 −0.0006 (0.0004) 0.10 216 −0.0006 (0.0004) 0.09
 Head circumference, cm 219 −0.03 (0.12) 0.78 217 −0.05 (0.12) 0.69
 Chest circumference, cm 219 −0.03 (0.14) 0.85 217 −0.06 (0.15) 0.69
 Waist circumference, cm 219 −0.06 (0.20) 0.75 217 −0.08 (0.20) 0.68
 Hip circumference, cm 219 −0.16 (0.27) 0.55 217 −0.20 (0.28) 0.46
 Mid-upper arm circumference, cm 217 0.37 (0.21) 0.08 215 0.38 (0.22) 0.08
 Biceps skinfold, mm 218 0.05 (0.07) 0.45 216 0.05 (0.07) 0.48
 Triceps skinfold, mm 218 −0.14 (0.10) 0.16 216 −0.15 (0.11) 0.15
a

Serum ferritin, natural log-transformed at enrolment (≤14 weeks gestation); beta (SE) is reported for continuous pregnancy outcomes; RR (95% CI) is reported for binary pregnancy outcomes

b

Models adjusted for gestational age of sample and vitamin B12 intervention

c

Models adjusted for gestational age of sample, vitamin B12 intervention, maternal BMI, standard of living index (SLI) >28, educational level, and ln(CRP)

d

Small for gestational age (SGA) was defined as birth weight < 10th percentile of the gestational age, using INTERGROWTH reference [17]