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. Author manuscript; available in PMC: 2023 Apr 22.
Published in final edited form as: Eur J Clin Nutr. 2019 Jul 11;74(1):112–125. doi: 10.1038/s41430-019-0464-3

Table 4C.

Associations between maternal serum ferritin concentrations at enrolment (Thurnham adjusted) and pregnancy and infant outcomes

Model 1b Model 2c


Variablesa n β (SE) or RR (95%CI) P-value n β (SE) or RR (95%CI) P-value
Pregnancy outcomes
 Birth weight, g 242 32.1 (30.5) 0.29 242 32.3 (29.9) 0.28
  Low birth weight (<2500 g), n (%) 242 0.95 (0.69, 1.31) 0.74 242 0.95 (0.69, 1.32) 0.77
 Gestational age at birth, weeks 248 0.14 (0.14) 0.30 248 0.15 (0.14) 0.28
  Preterm (<37 weeks), n (%) 248 0.83 (0.59, 1.16) 0.27 248 0.81 (0.57, 1.14) 0.22
 Preterm and low birth weight, n (%) 242 1.04 (0.63, 1.74) 0.87 242 1.03 (0.61, 1.71) 0.92
 Small for gestational aged, n (%) 241 0.93 (0.76, 1.12) 0.43 241 0.91 (0.74, 1.11) 0.35
Infant outcomes
 Haemoglobin, g/dl 68 0.28 (0.23) 0.23 68 0.33 (0.23) 0.16
  Anaemia (<11.0 g/dl), n (%) 68 0.77 (0.57, 1.03) 0.07 68 0.79 (0.60, 1.04) 0.09
 Length, cm 217 0.47 (0.20) 0.02 217 0.45 (0.20) 0.02
 Length-for-age z-score (LAZ) 215 0.17 (0.10) 0.07 215 0.16 (0.10) 0.10
  LAZ < −2 215 0.85 (0.69, 1.06) 0.14 215 0.87 (0.69, 1.09) 0.22
 Weight-for-age z-score (WAZ) 241 0.07 (0.07) 0.34 241 0.07 (0.07) 0.33
  WAZ < −2 241 0.89 (0.61, 1.28) 0.52 241 0.89 (0.62, 1.29) 0.55
 Weight-for-length z-score (WLZ) 177 −0.13 (0.14) 0.35 177 −0.12 (0.14) 0.37
  WLZ < −2 177 1.02 (0.71, 1.48) 0.90 177 1.06 (0.74, 1.53) 0.74
 BMI z-score (BMIZ) 214 −0.15 (0.11) 0.18 214 −0.14 (0.11) 0.18
  BMIZ < −2 214 1.07 (0.78, 1.47) 0.67 214 1.09 (0.80, 1.50) 0.58
 Ponderal Index, g/cm3 216 −0.0007 (0.0004) 0.06 216 −0.0007 (0.0004) 0.06
 Head circumference, cm 217 −0.05 (0.12) 0.70 217 −0.05 (0.12) 0.68
 Chest circumference, cm 217 −0.05 (0.14) 0.73 217 −0.06 (0.14) 0.70
 Waist circumference, cm 217 −0.07 (0.20) 0.72 217 −0.05 (0.20) 0.78
 Hip circumference, cm 217 −0.18 (0.27) 0.52 217 −0.20 (0.27) 0.46
 Mid-upper arm circumference, cm 215 0.33 (0.22) 0.13 215 0.36 (0.22) 0.09
 Biceps skinfold, mm 216 0.04 (0.07) 0.57 216 0.04 (0.07) 0.60
 Triceps skinfold, mm 216 −0.15 (0.11) 0.16 216 −0.15 (0.11) 0.15
a

Baseline serum ferritin concentrations were adjusted for inflammation using Thurnham [21, 22] methods; natural log-transformed; beta (SE) is reported for continuous pregnancy outcomes; RR (95%CI) is reported for binary pregnancy outcomes

b

Models adjusted for gestational age of sample and vitamin B12 intervention

c

Models adjusted for gestational age of sample, vitamin B12 intervention, maternal BMI, standard of living index (SLI) >28, educational level, and ln(CRP)

d

Small for gestational age (SGA) was defined by sex and gestational age <10th percentile using INTERGROWTH methods [17]