Table 3.
Pooled cohort equation-predicted 10-year ASCVD risk at baseline and 8 weeks after intervention overall and according to difference in individual risk factors, n = 437
| Control | F/V | DASH | F/V vs control | DASH vs control | DASH vs F/V | |
|---|---|---|---|---|---|---|
| Incorporating all risk factor differences | ||||||
| Baseline risk %, mean* (SE) | 1.84 (0.21) | 2.08 (0.23) | 1.69 (0.19) | n/a | n/a | n/a |
| 8-weekrisk %, mean* (SE) | 1.83 (0.21) | 1.88 (0.21) | 1.52 (0.17) | n/a | n/a | n/a |
| Absolute difference in risk from baseline and between groups, % difference (95% CI) | −0.01 (−0.09, 0.08) | −0.21 (−0.31, −0.10) | −0.17 (−0.26, −0.09) | −0.20 (−0.34, −0.06) | −0.17 (−0.28, −0.05) | −0.01 (−0.11,0.10) |
| Relative difference from baseline and between groups, % difference (95% CI) | −0.3 (−4.9, 4.5) | −9.9 (−14.0, −5.5) | −10.3 (−14.4, −5.9) | −9.6 (−15.5, −3.3) | −10.0 (−15.8, −3.7) | −0.4 (−6.9, 6.5) |
| Attributable difference in systolic blood pressure alone | ||||||
| Baseline mean (SE) | 1.84 (0.21) | 2.08 (0.23) | 1.69 (0.19) | n/a | n/a | n/a |
| 8-week mean (SE) | 1.79 (0.20) | 1.92 (0.22) | 1.44 (0.16) | n/a | n/a | n/a |
| Absolute difference from baseline and between groups, % (95% CI) | −0.05 (−0.11, 0.01) | −0.17 (−0.24, −0.09) | −0.25 (−0.32, −0.17) | −0.11 (−0.21, −0.01) | −0.20 (−0.29, −0.11) | −0.11 (−0.19, −0.04) |
| Relative difference from baseline and between groups, % (95% CI) | −2.7 (−5.9, 0.6) | −7.9 (−10.9, −4.8) | −14.6 (−17.3, −11.7) | −5.4 (−9.7, −0.9) | −12.2 (−16.2, −8.0) | −7.2 (−11.4, −2.7) |
| Attributable difference in total cholesterol alone | ||||||
| Baseline mean (SE) | 1.84 (0.20) | 2.08 (0.23) | 1.69 (0.19) | n/a | n/a | n/a |
| 8-week mean (SE) | 1.88 (0.21) | 2.08 (0.23) | 1.63 (0.18) | n/a | n/a | n/a |
| Absolute difference from baseline and between groups, % (95% CI) | 0.05 (−0.01, 0.10) | −0.00 (−0.07, 0.06) | −0.06 (−0.11, −0.01) | −0.06 (−0.15, 0.04) | −0.10 (−0.18, −0.02) | −0.06 (−0.13, 0.02) |
| Relative difference from baseline and between groups, % (95% CI) | 2.5 (−0.6, 5.7) | −0.2 (−3.2, 2.9) | −3.5 (−6.4, −0.5) | −2.6 (−6.7, 1.7) | −5.9 (−9.9, −1.7) | −3.3 (−7.4, 0.9) |
| Attributable differences in HDL cholesterol alone | ||||||
| Baseline mean (SD) | 1.84 (0.21) | 2.08 (0.23) | 1.69 (0.19) | n/a | n/a | n/a |
| 8-week mean (SD) | 1.83 (0.21) | 2.04 (0.23) | 1.84 (0.21) | n/a | n/a | n/a |
| Absolute difference from baseline and between groups, % (95% CI) | −0.00 (−0.06, 0.06) | −0.04 (−0.11, 0.03) | 0.15 (0.08, 0.21) | −0.04 (−0.13, 0.05) | 0.15 (0.07,0.23) | 0.18 (0.10, 0.27) |
| Relative difference from baseline and between groups, % (95% CI) | −0.0 (−3.2, 3.2) | −1.9 (−5.0, 1.2) | 8.8 (5.5, 12.3) | −1.9 (−6.1, 2.6) | 8.9 (4.1, 13.9) | 11.0 (6.1, 16.0) |
Estimates were generated using mixed-effects models with log-transformed 10-year ASCVD risk scores. Means and SE were exponentiated before presentation.
*
This estimate is the 10-year ASCVD risk score, which is the calculation of the 10-year risk of a cardiovascular event.