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. 2023 Apr 23;18:19. doi: 10.1186/s13062-023-00373-x

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — IGF2BP2 is highly expressed in colorectal cancer and correlates with the tumor stage. (A, B) Differences in IGF2BP2 expression between COAD tissue and normal tissue were analyzed using the GEPIA database (http://gepia.cancer-pku.cn/detail.php). (C) IGF2BP2 expression in para-carcinoma tissues and COAD tumor tissues at various clinical stages as determined by IHC analysis. (D) IGF2BP2 expression in 50 COAD tumor tissue samples (10 samples were stage I, 24 were stage II, and 16 were stage III-IV). (Student’s t- test). (E) IGF2BP2 expression in colorectal cancer tissues and adjacent normal tissues (n = 50). (paired t- test). *P < 0.05 and **** P < 0.0001