Table 3.
Reasons for Statin Nonuse, Stratified by Patient Characteristics, in the Deep Learning NLP Cohort
| Category | All | Statin nonusers per NLP | Statin nonusers stratified by reason for nonuse (N, % of statin nonusers) | P value | ||||
|---|---|---|---|---|---|---|---|---|
| Statin‐associated side effects, contraindications | Statin hesitancy | Clinical inertia | Guideline‐discordant practice | Nonspecific | ||||
| Total | 2703 | 2277 | 279 (12.2) | 428 (18.8) | 418 (18.4) | 442 (19.4) | 710 (31.1) | |
| Age, y | ||||||||
| 20–39 | 376 | 357 | 28 (7.8) | 38 (10.6) | 63 (17.6) | 93 (26.1) | 135 (37.8) | <0.001 |
| 40–75 | 2077 | 1753 | 212 (12.1) | 362 (20.7) | 338 (19.3) | 325 (18.5) | 516 (29.4) | |
| >75 | 250 | 167 | 39 (23.4) | 28 (16.8) | 17 (10.2) | 24 (14.4) | 59 (35.3) | |
| Sex | ||||||||
| Female | 1347 | 1140 | 163 (14.3) | 219 (19.2) | 192 (16.8) | 200 (17.5) | 366 (32.1) | <0.007 |
| Male | 1356 | 1137 | 116 (10.2) | 209 (18.4) | 226 (19.9) | 242 (21.3) | 344 (30.3) | |
| Race and ethnicity | ||||||||
| Non‐Hispanic White | 899 | 769 | 121 (15.7) | 173 (22.5) | 134 (17.4) | 127 (16.5) | 214 (27.8) | <0.001 |
| Non‐Hispanic Black | 218 | 192 | 17 (8.9) | 33 (17.2) | 46 (24.0) | 31 (16.1) | 65 (33.9) | |
| Hispanic | 430 | 352 | 48 (13.6) | 42 (11.9) | 69 (19.6) | 87 (24.7) | 106 (30.1) | |
| Non‐Hispanic Asian | 670 | 567 | 56 (9.9) | 110 (19.4) | 109 (19.2) | 103 (18.2) | 189 (33.3) | |
| Insurance provider | ||||||||
| Private | 1083 | 963 | 104 (10.8) | 193 (20.0) | 204 (21.2) | 161 (16.7) | 301 (31.3) | <0.001 |
| Medicare | 746 | 568 | 99 (17.4) | 119 (20.9) | 83 (14.6) | 91 (16.0) | 176 (31.0) | |
| Medicaid | 193 | 139 | 10 (7.2) | 16 (11.5) | 15 (10.8) | 64 (46.0) | 34 (24.5) | |
| Other | 402 | 360 | 35 (9.7) | 55 (15.3) | 69 (19.2) | 81 (22.5) | 120 (33.3) | |
| Diabetes type | ||||||||
| Type 1 | 202 | 186 | 16 (8.6) | 28 (15.0) | 27 (14.5) | 41 (22.0) | 74 (39.8) | 0.001 |
| Type 2 | 2501 | 2091 | 263 (12.6) | 400 (19.1) | 391 (18.7) | 401 (19.2) | 636 (30.4) | |
NLP indicates natural language processing.