Table 1.
Summary of Three Randomized Controlled Trials of Mechanical Cardiopulmonary Resuscitation Use in In‐Hospital Cardiac Arrest
| Author | Year | Design | Intervention | Device | Number of cases | Primary outcome | Results |
|---|---|---|---|---|---|---|---|
| Couper | 2021 | Multicenter, feasibility RCT | 3:1 Randomization mechanical vs manual CPR | Lund University Cardiopulmonary Assist System | 127 patients with IHCA | Proportion of eligible participants who were successfully randomized |
55% of eligible participants recruited. No difference when comparing rates of ROSC, survival to discharge, or survival with a good neurological outcome at 6 mo. |
| Halperin | 1993 | Single‐center RCT | 1:1 Randomization mechanical vs manual CPR | Thoracic‐vest system | 34 patients with IHCA | ROSC | ROSC rate higher in mechanical vs manual CPR (47% vs 18%). |
| Taylor | 1978 | Single‐center RCT | 1:1 Randomization mechanical vs manual CPR | Piston‐driven CPR device | 30 patients with IHCA | 1‐hour survival | No difference in 1‐hour survival between mechanical vs manual CPR (38% vs 42%) |