Table 4.
Mean Biomarker Values in Samples Drawn During Active Infections
| Biomarker | sC5b9, ng/mL | ANG2, pg/mL | ADAMTS13, % | VWF, % | Samples, n |
|---|---|---|---|---|---|
| No documented infection | 251 | 3452 | 93 | 267 | 161 |
| Any documented infection | 296 | 3752 | 85 | 275 | 36 |
| Gram-negative bacteremia | 357 | 3722 | 73 | 226 | 5 |
| Invasive aspergillosis | 307 | 3456 | 73 | 241 | 9 |
| BK viremia | 390 | 3975 | 63 | 343 | 5 |
| Human herpesvirus 6 | 395 | 4197 | 88 | 251 | 7 |
| Adenovirus | 303 | 3987 | 57 | 280 | 3 |
| Epstein-Barr virus | 313 | 3542 | 97 | 315 | 5 |
| Cytomegalovirus reactivation | 282 | 3984 | 85 | 280 | 19 |
The mean values of biomarkers from samples drawn within −3 to +7 days from the onset of the systemic infection are shown. There were 36 samples from 26 patients who had at least 1 infection and 161 samples from 55 patients without infections. There was heterogeneity of biomarker expression depending on the type of infection.