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Common Genes Associated with Pediatric PPGLs
| Cluster | Syndrome | Gene | PPGL type |
|---|---|---|---|
| Pseudohypoxia | Von-Hippel-Lindau | VHL | Pheo > PGL |
| Hereditary Paraganglioma-Pheochromocytoma Syndrome | SDHB | PGL (abdominal) > Pheo | |
| SDHD | PGL (head and neck) | ||
| SDHC | PGL (head and neck) | ||
| SDHA | PGL | ||
| Kinase | Multiple Endocrine Neoplasia Type 2 | RET | Pheo >> PGL |
| Neurofibromatosis Type 1 | NF-1 | Pheo |
