Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Model for Rep activity at elongating and stalled replication forks. (A) Rep stochastically associates with the replication fork during elongation. (B) Upon the replisome stalling, associated Rep molecules work to remove the roadblock from the path of the replication fork. This process is relatively quick. (C) Continuation of replication after the removal of the roadblock is slow, representing the rate-limiting step in resolution of the stalled state.
