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. 2023 Mar 3;51(7):e40. doi: 10.1093/nar/gkad097

Table 3.

Results on synthetic structures of length 80. The ‘# Correct’ is the number of correct solutions out of 1600. The ‘Correct Rate’ is the ratio of the number of correct solutions and 1600. The ‘Unique Solver’ column contains the number of structures for which a fitness function was the only fitness function to find a correct solution

Fitness function # Correct Correct rate GC-percent Unique solver
Ensemble defect 906 0.57 0.58 23
Free energy 14 0.01 0.77 0
Free energy (GC-controlled) 74 0.05 0.50 0
Probability 1185 0.74 0.59 218
Structure distance (BPD; arbitrary tie breaking) 353 0.22 0.50 0
Structure distance (BPD; average tie breaking) 406 0.25 0.50 0
Structure distance (BPD; minimum tie breaking) 268 0.17 0.50 1
Structure distance (HD; arbitrary tie breaking) 313 0.20 0.50 0
Structure distance (HD; average tie breaking) 428 0.27 0.50 2
Structure distance (HD; minimum tie breaking) 241 0.15 0.50 1
Structure distance (INF; arbitrary tie breaking) 331 0.21 0.50 1
Structure distance (INF; average tie breaking) 393 0.25 0.50 0
Structure distance (INF; minimum tie breaking) 258 0.16 0.50 2