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. 2023 Mar 13;51(7):3452–3464. doi: 10.1093/nar/gkad151

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© The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Graphical Abstract — MIRELLA is a resource-aware mathematical model that by combining experimental data and simulations unveils the molecular mechanisms underlying the reallocation of cellular resources as a consequence of miRNAs activity.