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. 2023 Apr 10;14:1094359. doi: 10.3389/fphys.2023.1094359

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Copyright © 2023 Sato, Goto, Yamanouchi and Sakurai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Phenotypic analysis of the skeletal muscles of DMD nude rats. (A) The percentage of body weight represented by each muscle tissue at the indicated ages in WT and DMD nude rats. N.S. non-significant, *p < 0.05. (B) Histological changes in the fiber diameter in 12-month-old WT and DMD nude rats. (C) Representative images of hematoxylin & eosin (H&E) staining of the tibialis anterior (TA), quadriceps, and gastrocnemius muscle sections in 12-month-old WT and DMD nude rats. The symbols, ➡, ▼, and ▽, indicate necrotic myofibers, fibrosis, and adipogenesis, respectively. Scale bar = 50 µm.