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DZSM downregulated CXCR4 and CXCR12 expression and inhibited inflammatory cytokine production. (A) RT-PCR, ELISA, and IF analysis of CXCR4 (Bar length: 50 μm); (B) RT-PCR, ELISA, and IF analysis of CXCL12 (Bar length: 50 μm); (C) Analysis of IL-1β, IL-6, TNF-α, and IL-18 levels by ELISA. (D) RT-PCR analysis of IL-1β, IL-6, TNF-α, and IL-18 (compared with the Nor group: # p < 0.05, ## p < 0.01; compared with the Aging group: * p < 0.05, ** p < 0.01).
