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. 2023 Mar 29;26(4):106509. doi: 10.1016/j.isci.2023.106509

Figure 1.

Figure 1

Characterization of regulatory regions around Nkx2-5 during early heart development

RNA-seq tracks for E8.25 (EBI: ERR332388), E9.5 (GEO: GSE104670), E12.5 (GEO: GSE82471), and E16.5 (GEO: GSE78317) hearts were in red. H3K27ac ChIP-seq tracks for E9.5 OFT, E12.5 (GEO: GSE82449), and E16.5 (GEO: GSE82973) hearts were in purple. The AR1, AR2, and AR3 enhancers (Schwartz & Olson, 1999) were in magenta, and the G-S enhancer (III et al., 2004) was in orange, as well as the UH5 and UH6 enhancers (Chi et al., 2005) were in red and blue, respectively. The newly identified U1 and U2 enhancers were in light green and light blue, respectively. OFT, outflow tract. See also Figure S1.