Table 1.

Summary of included studies.

ID	Title	Design	Inclusion criteria	Type of ablation	Device used	length of follow up (month)
GULLETTA 2013	Safety and Efficacy of Open Irrigated-Tip Catheter Ablation of Wolff-Parkinson-White Syndrome in Children and Adolescents	Cohort	Patients less than 18 years old who were referred to San Raffaele Hospital for catheter ablation of WPW between January 2010 and July 2011. a history of paroxysmal tachycardia or syncope. inducible supraventricular tachycardia at the electrophysiologic study. a preexcited RR interval <250 ms during induced atrial fibrillation. an effective refractory period of the AP < 240 ms.	Radiofrequency ablation,	open irrigatedtip catheter (Celsius Thermocool 3.5 mm, 7 F, Btype, Biosense Webster, Diamond Bar, CA, USA)	12
P. DiLorenzo 2012	Ablating the anteroseptal accessory pathway—ablation via the right internal jugular vein may improve safety and efficacy	Cohort	patients less than 21 years of age, who had an accessory pathway in the anteroseptal region of the tricuspid annulus (either concealed AP or WPW), and underwent radiofrequency (RF) or cryoablation (cryo) with the ablation catheter approaching the anteroseptal region via the right internal jugular vein (RIJV).	Radiofrequency,	a 4-mm tip 7Fr EZ Steer Ablation Catheter (Biosense Webster, Diamond Bar, CA, USA) in all cases except in patients weighing less than 20 kg, where a 4-mm tip 5Fr Medtronic Attacker Ablation Catheter (Medtronic, Minneapolis, MN, USA) Cryoablation, 6-mm tip Cryocatheter (Medtronic)	15
Ceresnak 2015	Success Rates in Pediatric WPW Ablation Are Improved with 3-Dimensional Mapping Systems Compared with Fluoroscopy Alone: A Multicenter Study	Cohort	All patients 21 years of age with WPW who underwent invasive EP testing and ablation between 2008 and 2012	Radiofrequency or Cryoablation,	Biosense Webster (NaviStar, Diamond Bar, CA, USA) or Boston Scientific (Blazer, Marlborough, MA, USA) 7 French 4 mm tip catheters.	17
Brado 2021	Outcomes of ablation in Wolff-Parkinson-White-syndrome: Data from the German Ablation Registry	Cohort	admissions for catheter ablation of supraventricular or ventricular arrhythmias, all consented patients between January 2007 and January 2010	Radiofrequency or Cryoablation,	Biosense Webster (NaviStar, Diamond Bar, CA, USA) or Boston Scientific (Blazer, Marlborough, MA, USA) 7 French 4 mm tip catheters.	12
Pietrzak 2020	Success rate and safety of catheter ablation in preexcitation syndrome: A comparison between adult and pediatric patients	Cohort	Patients with WPW were referred to electrophysiological study (EPS) and CA between 2016 and 2017	Radiofrequency:	irrigated tip ablation — power control mode (temperature limit 48 °C, power limit of 30 W; Navistar ThermoCool, Biosense Webster, Diamond Bar, CA, USA)	–
Lin 2019	Trend and risk factors of recurrence and complications after arrhythmias radiofrequency catheter ablation: a nation-wide observational study in Taiwan	Cohort	all targeted patients with arrhythmia who received first RFCA from 2001 to 2010. The targeted arrhythmias were PSVT (International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9 CM) Code 4270), WPW (426.7), AFL (427.32), AF (427.31) and VT (427.1),	Radiofrequency	–	51.6
HOCINI 2015	Focal Arrhythmia Ablation Determined by High-Resolution Noninvasive Maps: Multicenter Feasibility Study	Cohort	patients with symptomatic premature ventricular complexes (PVCs), atrial tachycardia (AT), and manifest accessory pathway (WPW syndrome) were prospectively included at 3 centers (France, England, and Germany).	Radiofrequency,	4-mmtip (Biosense-Webster, Diamond Bar, CA, USA) ablation catheter	24.7
T. Brown 2021	Ablation of manifest septal accessory pathways: a single-center experience	Cohort	Patients undergoing an electrophysiologic study (EPS) with a manifest SAP were identified from a chart review between January of 2008 and August of 2019	Radiofrequency and cryoablation	, large curve 4-mm tip ablation catheter (Blazer™ Boston Scientific, Marlborough, MA). But for 2 AP used 8-mm RF ablation catheter	21.5
Mudrić 2019	Six-month success of radiofrequency ablation in cardiac arrhythmias treatment – experience of our centre	Cohort	consecutive patients with different cardiac arrhythmias in which RFA was performed during 2014 at the Institute for Cardiovascular Diseases “Dedinje”, Belgrade, Serbia,.	Radiofrequency	–	6
Fujino 2020	Clinical characteristics of challenging catheter ablation procedures in patients with WPW syndrome: A 10 year single-center experience	Cohort	symptomatic consecutive WPW patients who underwent a catheter ablation procedure to eliminate an AP at between August 2005 and December 2015	Radiofrequency and cryoablation,	4-mm non-irrigated tip ablation catheter (BlazerTMII; Boston Scientific, San Jose, CA, USA for right sided ablation or Celsius; Biosense Webster, Diamond Bar, CA, USA for left sided ablation), 7-Fr 6-mm electrode tip cryoablation catheter (Freezor1 Xtra, CryoCath; Medtronic Inc., Minneapolis, MN, USA), Cryoablation, 7-Fr 6-mm electrode tip cryoablation catheter (Freezor1 Xtra, CryoCath; Medtronic Inc., Minneapolis, MN, USA)	99.6
Uhm 2018	Accessory pathway-related left ventricular wall motion abnormality and the effects of radiofrequency catheter ablation in patients with Wolff-Parkinson-White syndrome	Cohort	consecutive patients with WPW syndrome who underwent pre-RFCA echocardiography and RFCA for AP at a university hospital between January 2011 and May 2017	Radiofrequency,	–	6